To identify truly significant trends, look for three signals: 1) a deep and broad 'possibility space' with many potential intersections; 2) a high rate of discovery and accelerating momentum; and 3) the creation of new language because existing words are insufficient to describe what's happening.

Instead of incremental planning, run "megatrend workshops" to identify major societal or technological shifts 15-20 years out. By working backward from that inevitable future, you can define what your company needs to do in 5 years, and therefore what you must invest in today.

To vet ambitious ideas like self-sailing cargo ships, first ask if they are an inevitable part of the world in 100 years. This filters for true long-term value. If the answer is yes, the next strategic challenge is to compress that timeline and build it within a 10-year venture cycle.

The most profitable periods for trend following occur when market trends extend far beyond what seems rational or fundamentally justified. The strategy is designed to stay disciplined as prices move to levels few can imagine, long after others have exited.

The rapid pace of AI innovation means today's cutting-edge research is irrelevant in three months. This creates a core challenge for founders: establishing a stable, long-term company vision when the underlying technology is in constant, rapid flux. The solution is to anchor on the macro trend, not the specific implementation.

Brad Jacobs's mentor taught him that correctly identifying long-term trends is paramount. You can excel at execution, but if you're swimming against the major current, you won't create significant value. This principle guided Jacobs in selecting industries for his eight billion-dollar companies.

The most effective investment strategy is to first identify a growing consumer category with strong tailwinds (e.g., Mediterranean food). Only then should you invest in or build the company with the potential to become the dominant player, capitalizing on the winner-take-all dynamics of the industry.

The vague advice to 'live in the future' becomes practical when you use emerging tech (like AI agents in 2022) to solve your own business problems. By being an early adopter, you encounter the novel challenges that the mass market will face in 1-2 years, revealing the next wave of demand before it's obvious.

Instead of predicting short-term outcomes, focus on macro trends that seem inevitable over a decade (e.g., more e-commerce, more 3D interaction). This framework, used by Tim Ferriss to invest in Shopify and by Roblox for mobile, helps identify high-potential areas and build with conviction.