/
© 2026 RiffOn. All rights reserved.

Get your free personalized podcast brief

We scan new podcasts and send you the top 5 insights daily.

  1. This Week in Startups
  2. This Startup Fused Human Brain Cells with Silicon Chips | E2295
This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups · Jun 1, 2026

Cortical Labs is fusing human brain cells with silicon chips, creating biological data centers 5000x more efficient at reinforcement learning.

For Hardware Startups, a Flying Prototype Represents Only 1% of the Total Work

Drone company Pika stresses that going from an initial working prototype to a commercially viable product that customers can rely on for daily, intensive operations constitutes 99% of the development effort.

This Startup Fused Human Brain Cells with Silicon Chips | E2295 thumbnail

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups·a day ago

Cortical Labs Draws an Ethical Red Line at Creating Conscious Systems to Prevent Suffering

The company's core ethical principle is to avoid creating conscious systems because consciousness implies the capacity to suffer, which they explicitly want to prevent their technology from causing.

This Startup Fused Human Brain Cells with Silicon Chips | E2295 thumbnail

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups·a day ago

Deep Tech Startups Must Proactively Engage Bioethicists and Critics, Even the Vatican

Cortical Labs preemptively addressed ethical concerns about fusing neurons with chips by engaging directly with bioethicists and religious institutions, which helped them navigate potential backlash and build trust.

This Startup Fused Human Brain Cells with Silicon Chips | E2295 thumbnail

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups·a day ago

Military Drones That Are "Too Nice" and Reliable Make Poor Kinetic Weapons

Pika's drones are designed for high reliability and low operating costs, making them ideal for logistics but ill-suited for kinetic (bombing) missions, which favor cheaper, more disposable designs.

This Startup Fused Human Brain Cells with Silicon Chips | E2295 thumbnail

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups·a day ago

Pika Vertically Integrates Hardware and Software to Create an Apple-Like User Experience

By designing and owning critical components like motors, batteries, and software in-house, Pika delivers a simple, integrated user experience for its complex drones, a strategy used by companies like Apple and Tesla.

This Startup Fused Human Brain Cells with Silicon Chips | E2295 thumbnail

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups·a day ago

Cortical Labs' On-Site Neuron Labs Decouple Biological Data Centers From Chip Supply Chains

By growing neurons for their biological computers directly at data center locations, Cortical Labs creates a self-sufficient, decentralized model, eliminating reliance on a central hardware vendor and its supply chain.

This Startup Fused Human Brain Cells with Silicon Chips | E2295 thumbnail

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups·a day ago

Simple Organisms Possess a "Generalised Intelligence" Lacking in Today's Super-Intelligent AIs

While AIs can solve complex computational problems, they lack the generalized intelligence of a simple fly, which can navigate novel, unpredictable environments—a key test for true AGI that current models fail.

This Startup Fused Human Brain Cells with Silicon Chips | E2295 thumbnail

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups·a day ago

Drone Startups Pika and Zipline Use Lenient Foreign Regulations to Prove Their Tech

Strict US FAA rules on beyond-visual-line-of-sight operations force autonomous drone companies to deploy commercially in countries like Brazil and Rwanda, which have more permissive regulatory environments to gather data.

This Startup Fused Human Brain Cells with Silicon Chips | E2295 thumbnail

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups·a day ago

Pika's Ag-Drones' Real ROI is Precise Application, Not Just Lower Operating Costs

While autonomous drones save on fuel and labor, their biggest selling point is applying chemicals more precisely. This reduces waste of expensive materials, which can be four times the cost of the application service itself.

This Startup Fused Human Brain Cells with Silicon Chips | E2295 thumbnail

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups·a day ago

Pika Built Its New Military Drone Based on Direct User Feedback, Not Formal Requirements

Instead of waiting for a formal requirements document, Pika developed its Dropship drone based on direct, actionable feedback from military users (Air Force, Army) on a prior model, accelerating the design cycle.

This Startup Fused Human Brain Cells with Silicon Chips | E2295 thumbnail

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups·a day ago

Biological Computers Are 5,000x More Sample-Efficient Than GPUs for Reinforcement Learning

Cortical Labs' neuron-based systems require 5,000 times fewer steps than GPU systems to learn goal-seeking behaviors, a massive advantage for real-world robotics where time cannot be accelerated.

This Startup Fused Human Brain Cells with Silicon Chips | E2295 thumbnail

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups·a day ago

Cortical Labs Uses a Cloud Platform to Democratize Access, Mirroring NVIDIA's CUDA Strategy

Instead of only selling expensive hardware, Cortical Labs offers a cloud platform. This strategy lowers the accessibility barrier, enabling developers without labs to experiment and innovate, much like NVIDIA did with its free CUDA software.

This Startup Fused Human Brain Cells with Silicon Chips | E2295 thumbnail

This Startup Fused Human Brain Cells with Silicon Chips | E2295

This Week in Startups·a day ago