When working in complex organizations like the UN or federal government, don't try to master their internal language. Instead, find and partner with internal experts who can translate your goals into the organization's native operating system to achieve impact.

The National Defense Authorization Act (NDAA) has elevated biotech to a national security asset, alongside AI and quantum computing. This shift creates new funding opportunities through a dedicated Department of Defense (DOD) biotech office, distinct from traditional NIH grants.

Superhuman's CTO credits a non-tech role managing submarine maintenance with teaching him to lead without technical legitimacy. By being forced to put his ego aside and drive change by asking fundamental questions, he learned to influence people far smarter in their domain.

Luckey reveals that Anduril prioritized institutional engagement over engineering in its early days, initially hiring more lawyers and lobbyists. The biggest challenge wasn't building the technology, but convincing the Department of Defense and political stakeholders to believe in a new procurement model, proving that shaping the system is a prerequisite for success.

Scientists in specialized roles like immunogenicity risk becoming siloed service providers. To maintain impact and growth, they must proactively collaborate with other functions like CMC, safety, and quality. This provides a holistic view of drug development and integrates their expertise into the entire process.

Innovation capital is the credibility needed to win support for unproven ideas. Even top leaders like Salesforce's CEO Mark Benioff consciously build this capital, demonstrating that authority alone is insufficient to drive major innovation initiatives.

The most satisfying outcome of influence is not receiving credit, but witnessing a colleague who initially resisted your idea later advocate for it with conviction, believing it to be their own. This indicates you've planted a seed that grew into genuine alignment, not forced compliance.

Navigating a large military organization is like enterprise sales. Success depends not on an idea's merit, but on understanding the political landscape: each player's influence, incentives, and how they interact to enable or block a decision.

To drive rapid change within the Department of Energy, Carl Coe prioritized building alliances with existing employees. Instead of forcing his way in, he spent significant time getting to know people and respecting the organization. This opened doors and fostered cooperation, which was critical for long-term success.