Periods of intense technological disruption, like the current AI wave, destabilize established hierarchies and biases. This creates a unique opportunity for founders from non-traditional backgrounds who may be more resilient and can identify market needs overlooked by incumbents.

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When evaluating AI startups, don't just consider the current product landscape. Instead, visualize the future state of giants like OpenAI as multi-trillion dollar companies. Their "sphere of influence" will be vast. The best opportunities are "second-order" companies operating in niches these giants are unlikely to touch.

Unlike cloud or mobile, which incumbents initially ignored, AI adoption is consensus. Startups can't rely on incumbents being slow. The new 'white space' for disruption exists in niche markets large companies still deem too small to enter.

Unlike previous tech waves that trickled down from large institutions, AI adoption is inverted. Individuals are the fastest adopters, followed by small businesses, with large corporations and governments lagging. This reverses the traditional power dynamic of technology access and creates new market opportunities.

The democratization of technology via AI shifts the entrepreneurial goalpost. Instead of focusing on creating a handful of billion-dollar "unicorns," the more impactful ambition is to empower millions of people to each build a million-dollar "donkey corn" business, truly broadening economic opportunity.

AI is not solely a tool for the powerful; it can also level the playing field. Grassroots political campaigns and labor organizers can use AI to access capabilities—like personalized mass communication and safety reporting apps—that were previously only affordable for well-funded, established entities.

In rapidly evolving markets like AI, founders often fall into psychological traps, such as feeling they are too late or that funding has dried up. However, the current environment offers unprecedented organic user demand and technological leverage, making it an ideal time to build if you can ignore the noise.

AI drastically accelerates the ability of incumbents and competitors to clone new products, making early traction and features less defensible. For seed investors, this means the traditional "first-mover advantage" is fragile, shifting the investment thesis heavily towards the quality and adaptability of the founding team.

When evaluating revolutionary ideas, traditional Total Addressable Market (TAM) analysis is useless. VCs should instead bet on founders with a "world-bending vision" capable of inducing a new market, not just capturing an existing one. Have the humility to admit you can't predict market size and instead back the visionary founder.

For the first time, a disruptive technology's most advanced capabilities are available to the public from day one via consumer apps. An individual with a smartphone has access to the same state-of-the-art AI as a top VC or Fortune 500 CEO, making it the most democratic technology in history.

Conventional venture capital wisdom of 'winner-take-all' may not apply to AI applications. The market is expanding so rapidly that it can sustain multiple, fast-growing, highly valuable companies, each capturing a significant niche. For VCs, this means huge returns don't necessarily require backing a monopoly.