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  1. The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch
  2. 20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening
20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch · Nov 13, 2025

VCs grapple with AI's breakneck pace, as Sequoia's shakeup signals a new era. Defensibility is fleeting, while AI agents promise huge upside.

True Revenue Unlock: AI as a Teammate, Not a Tool

The transition from AI as a productivity tool (co-pilot) to an autonomous agent integrated into team workflows represents a quantum leap in value creation. This shift from efficiency enhancement to completing material tasks independently is where massive revenue opportunities lie.

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening thumbnail

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch·3 months ago

AI-Powered Clones Erode Early-Stage Moats

AI drastically accelerates the ability of incumbents and competitors to clone new products, making early traction and features less defensible. For seed investors, this means the traditional "first-mover advantage" is fragile, shifting the investment thesis heavily towards the quality and adaptability of the founding team.

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening thumbnail

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch·3 months ago

AI's Pace Creates Rapid Knowledge Obsolescence

In the current AI landscape, knowledge and assumptions become obsolete within months, not years. This rapid pace of evolution creates significant stress, as investors and founders must constantly re-educate themselves to make informed decisions. Relying on past knowledge is a quick path to failure.

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening thumbnail

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch·3 months ago

Sequoia's Shake-Up: A Barometer for Universal VC Anxiety in AI

The leadership change at Sequoia, arguably the world's top venture firm, is a strong indicator of the intense pressure the entire VC industry faces. It reflects a fear of falling behind in the AI race and the brutal reality that even the best are struggling to adapt to the new competitive landscape.

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening thumbnail

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch·3 months ago

VCs Must Diversify Portfolios to Counter AI-Era Risk

The increased volatility and shorter defensibility windows in the AI era challenge traditional VC portfolio construction. The logical response to this heightened risk is greater diversification. This implies that early-stage funds may need to be larger to support more investments or write smaller checks into more companies.

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening thumbnail

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch·3 months ago

Venture Funding is Now a Binary Game: Hot or Not

The current fundraising environment is the most binary in recent memory. Startups with the "right" narrative—AI-native, elite incubator pedigree, explosive growth—get funded easily. Companies with solid but non-hype metrics, like classic SaaS growers, are finding it nearly impossible to raise capital. The middle market has vanished.

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening thumbnail

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch·3 months ago

Betting Against the AI Boom is a Loser's Game of Timing

While the AI capex boom may seem unsustainable, the mechanics of shorting it (e.g., buying puts) reveal the extreme difficulty of the trade. The bet requires being correct not just on the eventual downturn but on its precise timing. The risk of losing the entire premium makes it an unattractive risk-adjusted bet.

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening thumbnail

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch·3 months ago

Top Founders Cultivate, They Don't "Run a Process"

The most effective fundraising strategy isn't a rigid, time-boxed "process." Instead, elite founders build genuine relationships with target VCs over months. When it's time to raise, the groundwork is laid, turning the fundraise into a quick, casual commitment rather than a competitive, game-driven event.

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening thumbnail

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch·3 months ago

The Two Viable AI Business Models: Attach to Compute or Replace Humans

In the current market, AI companies see explosive growth through two primary vectors: attaching to the massive AI compute spend or directly replacing human labor. Companies merely using AI to improve an existing product without hitting one of these drivers risk being discounted as they lack a clear, exponential growth narrative.

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening thumbnail

20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch·3 months ago