Similar to the dot-com era, the current AI investment cycle is expected to produce a high number of company failures alongside a few generational winners that create more value than ever before in venture capital history.

As AI infrastructure giants become government-backed utilities, their investment appeal diminishes like banks after 2008. The next wave of value creation will come from stagnant, existing businesses that adopt AI to unlock new margins, leveraging their established brands and distribution channels rather than building new rails from scratch.

Like containerization, AI is a transformative technology where value may accrue to customers and users, not the creators of the core infrastructure. The biggest fortunes from containerization were made by companies like Nike and Apple that leveraged global supply chains, not by investors in the container companies themselves.

The true financial windfall from AI won't come from hyped, "AI-native" companies like OpenAI. Instead, established giants like Meta and Amazon will generate massive shareholder value by applying AI to optimize their existing, scaled operations in areas like ad targeting, logistics, and robotics.

If AI is truly transformational, its greatest long-term value will accrue to non-tech companies that adopt it to improve productivity. Historical tech cycles show that after an initial boom, the producers of a new technology are eventually outperformed by its adopters across the wider economy.

When a new technology stack like AI emerges, the infrastructure layer (chips, networking) inflects first and has the most identifiable winners. Sacerdote argues the application and model layers are riskier and less predictable, similar to the early, chaotic days of internet search engines before Google's dominance.

In 2026, the AI investment narrative will expand from foundational model creators to companies building applications and services. It also includes sectors enabling AI growth, such as energy generation and data centers, offering a wider range of investment opportunities beyond the initial tech giants.

The AI investment case might be inverted. While tech firms spend trillions on infrastructure with uncertain returns, traditional sector companies (industrials, healthcare) can leverage powerful AI services for a fraction of the cost. They capture a massive 'value gap,' gaining productivity without the huge capital outlay.

Conventional venture capital wisdom of 'winner-take-all' may not apply to AI applications. The market is expanding so rapidly that it can sustain multiple, fast-growing, highly valuable companies, each capturing a significant niche. For VCs, this means huge returns don't necessarily require backing a monopoly.