Don't unleash a generic AI agent on your entire database. To get high response rates, segment contacts into specific sub-personas based on role, behavior, or status (e.g., churn risk). Then, train dedicated sub-agents or campaigns for each persona, allowing for true personalization at scale in batches of around 1,000 contacts.

Personalization is not one-size-fits-all. Director-level and above prospects are 50% more likely to respond to company-level relevance (e.g., business initiatives). In contrast, individual contributors and managers are more receptive to individual-level personalization.

Combine two specific audience identifiers in your subject line, like role and company attribute ("Mid-market CMOs") or interest and a pain point ("Beauty fans with sensitive skin"). This "double personalization" tactic reportedly increases B2B open rates by 24% and B2C by 29% by making the message feel hyper-relevant.

Modern AI enables hyper-personalization where every email element—copy, images, discounts—is generated uniquely for each shopper based on real-time site behavior. This moves beyond simple segmentation to a one-to-one communication standard.

Stop trying to convert customers directly within an email. An email's primary function is to provide enough evidence and intrigue to earn a click through to a dedicated sales page. The sales page, not the email, is responsible for the final conversion. This shift makes copy more conversational and less pushy.

Tools like Lovable.dev allow marketing teams to create functional, niche-specific landing pages with payment collection simply by describing them. Instead of one generic page, you can instantly build a tailored experience for a segment like "plumbers in the Midwest," drastically increasing campaign relevance and speed.

To achieve personalization efficiently, Samsung creates a few core email templates. They then use third-party tools like Movable Ink to dynamically insert content modules based on individual customer data, such as products owned or purchase propensity. This avoids massive versioning complexity.

Move beyond traditional sales sequences by implementing "invisible funnels" triggered by customer actions, like filling out an intake form. Use automation to analyze their responses and initiate personalized conversations, creating trust and generating sales without a hard-sell campaign.

Instead of getting paralyzed by data, begin segmenting by simply listing anecdotal observations on paper. Note patterns from customer conversations, email replies, and surveys to generate initial hypotheses about your audience buckets. This practical first step makes segmentation far more approachable.