AI's most significant impact is not just campaign optimization but its ability to break down data silos. By combining loyalty, e-commerce, and in-store interaction data, retailers can create a holistic customer view, enabling truly adaptive and intelligent marketing across all channels.

LLMs have hit a wall by scraping nearly all available public data. The next phase of AI development and competitive differentiation will come from training models on high-quality, proprietary data generated by human experts. This creates a booming "data as a service" industry for companies like Micro One that recruit and manage these experts.

The next evolution in personalized medicine will be interoperability between personal and clinical AIs. A patient's AI, rich with daily context, will interface with their doctor's AI, trained on clinical data, to create a shared understanding before the human consultation begins.

The next leap in biotech moves beyond applying AI to existing data. CZI pioneers a model where 'frontier biology' and 'frontier AI' are developed in tandem. Experiments are now designed specifically to generate novel data that will ground and improve future AI models, creating a virtuous feedback loop.

AI serves as a powerful health advocate by holistically analyzing disparate data like blood work and symptoms. It provides insights and urgency that a specialist-driven system can miss, empowering patients in complex, under-researched areas to seek life-saving care.

Text descriptions of physical pain are often vague. To improve an AI coach's helpfulness, use multi-modal inputs. Uploading a photo and circling the exact point of pain or a video showing limited range of motion provides far more precise context than words alone.

An effective AI strategy in healthcare is not limited to consumer-facing assistants. A critical focus is building tools to augment the clinicians themselves. An AI 'assistant' for doctors to surface information and guide decisions scales expertise and improves care quality from the inside out.

The effectiveness of an AI system isn't solely dependent on the model's sophistication. It's a collaboration between high-quality training data, the model itself, and the contextual understanding of how to apply both to solve a real-world problem. Neglecting data or context leads to poor outcomes.

Instead of replacing experts, AI can reformat their advice. It can take a doctor's diagnosis and transform it into a digestible, day-by-day plan tailored to a user's specific goals and timeline, making complex medical guidance easier to follow.