While technical challenges exist, an audience poll reveals that for 65% of organizations, "people problems"—such as fear, resistance to change, and lack of buy-in—are the primary obstacles hindering successful AI implementation.

A key challenge in AI adoption is not technological limitation but human over-reliance. 'Automation bias' occurs when people accept AI outputs without critical evaluation. This failure to scrutinize AI suggestions can lead to significant errors that a human check would have caught, making user training and verification processes essential.

Implementing AI is becoming less of a technical challenge and more of a human one. The key difficulties are in managing change, helping people adapt to new workflows, and overcoming resistance, making skills like design thinking and lean startup crucial for success.

Before implementing AI automation, you must validate and refine a process manually. Applying AI to a flawed system doesn't fix it; it just makes the system fail more efficiently and at a larger scale, wasting significant time and resources.

Companies fail to generate AI ROI not because the technology is inadequate, but because they neglect the human element. Resistance, fear, and lack of buy-in must be addressed through empathetic change management and education.

Leaders often misjudge their teams' enthusiasm for AI. The reality is that skepticism and resistance are more common than excitement. This requires framing AI adoption as a human-centric change management challenge, focusing on winning over doubters rather than simply deploying new technology.

Many AI projects become expensive experiments because companies treat AI as a trendy add-on to existing systems rather than fundamentally re-evaluating the underlying business processes and organizational readiness. This leads to issues like hallucinations and incomplete tasks, turning potential assets into costly failures.

Adopting AI acts as a powerful diagnostic tool, exposing an organization's "ugly underbelly." It highlights pre-existing weaknesses in company culture, inter-departmental collaboration, data quality, and the tech stack. Success requires fixing these fundamentals first.

The primary barrier to successful AI implementation in pharma isn't technical; it's cultural. Scientists' inherent skepticism and resistance to new workflows lead to brilliant AI tools going unused. Overcoming this requires building 'informed trust' and effective change management.