At a crisis-ridden Reddit, investors wanted Katelin Holloway to “add process.” She realized the core issue was a broken social contract among employees. Her first priority was restoring trust and a shared identity, which then enabled high-leverage process and systems work.

Getting a partnership deal done requires more than a good pitch; it requires an internal advocate. Leaders should leverage their network to identify and cultivate a champion inside the target company. This person is critical for navigating internal bureaucracy and pushing the deal over the goal line, as "there's a million ways for deals to die."

A successful acquisition strategy goes beyond the highest bid. It involves 'thinking like the molecule'—evaluating which buyer has the specific expertise, capabilities, and cultural alignment to best steward the asset's development. This reframes M&A from a financial transaction to a decision about the asset's future.

To regain mindshare from neglected partners, focus on a "ground game." Start by showing up and listening, then deliver quick, tangible wins like unblocking a renewal or simplifying a painful process. Consistent follow-through rebuilds trust and mindshare faster than most leaders expect.

When traditional outreach for a licensing deal failed, Dr. Holman had 80 patients send personal Christmas cards to the CEO of Boehringer Ingelheim. The highly personal, non-digital approach bypassed corporate handlers, landed directly on the CEO's desk, and secured a meeting within a week.

After working out 22 distressed joint ventures during the GFC, the key lesson was that partner quality dictates outcomes more than the deal itself. When things go wrong, good partners collaborate to find solutions, while bad partners create conflict, making even a good deal untenable.

When hypergrowth causes you to fail internal stakeholders (like Operations), apologies are insufficient. Rebuild trust by going to the CEO and board *together* with the slighted team to advocate for a drastic roadmap pivot that prioritizes their needs, demonstrating true commitment to their success.

Vivtex's $2.1B deal with Novo Nordisk wasn't from a single pitch; it was cultivated over many years, stemming from pre-existing academic relationships. The key was building mutual scientific trust by consistently sharing progress—and even failures—allowing Novo Nordisk to observe their journey long-term.

During M&A integration, conflict arises when teams defend their respective solutions. Re-center the conversation on the customer problem they both aimed to solve. Emphasizing that all solutions are temporary and fungible de-escalates conflict and fosters alignment around a shared, permanent goal.