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  1. Business Of Biotech
  2. Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.
Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech · Mar 2, 2026

Vivtex CEO Thomas von Erlach on developing orally available biologics, spinning out of Langer's lab, and securing a $2.1B Novo Nordisk deal.

Biotech Spinouts Must Shift from Publishing Data to Industry-Grade Validation

Moving technology from academia to a startup requires a crucial mindset shift. The academic goal of publishing data must be replaced by the industry requirement of extensive validation. For Vivtex, this single piece of advice added years of work but was essential for creating a commercially viable platform.

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Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

Technical Founders Becoming CEOs Should Immediately Hire an Experienced Operations Lead

When Vivtex's scientific founder became CEO, his most critical move was hiring an experienced finance and operations leader. This structure allows the CEO to leverage deep technical insight for strategic partnerships, while delegating operational complexities they are less equipped to handle.

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Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

Deep-Tech Startups Use Stealth Mode to Finalize Technology Applications, Not to Hide

Vivtex used stealth mode not for secrecy, but to give itself a 'time window' to fully develop its technology and nail down its precise application. This prevented them from making public promises they might later have to retract, ensuring a more stable and confident market entry.

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Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

Biotech Startups Can Achieve Profitability Through a Portfolio of Pharma Partnerships

Vivtex funded its growth and reached profitability not through traditional VC rounds, but by securing around 10 early pharma partnerships. This strategy provided significant non-dilutive revenue, reducing their reliance on investors and giving them more control over their trajectory—a powerful alternative to the typical biotech funding model.

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Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

Multi-Billion Dollar Pharma Deals Emerge From Years of Scientific Trust-Building

Vivtex's $2.1B deal with Novo Nordisk wasn't from a single pitch; it was cultivated over many years, stemming from pre-existing academic relationships. The key was building mutual scientific trust by consistently sharing progress—and even failures—allowing Novo Nordisk to observe their journey long-term.

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Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

Startups Must Keep Critical R&D In-House Because CROs Can't Match Survival-Driven Pace

Vivtex avoids outsourcing critical R&D because external partners and CROs cannot match the speed of a startup team whose very existence depends on solving problems quickly. This internal urgency is a core competitive advantage that is lost when relying on third parties with different priorities.

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D. thumbnail

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

MIT's Bob Langer Pushes Postdocs to Solve Big, Risky Problems, Sparking Startups

Top academic mentors like MIT's Dr. Robert Langer guide postdocs away from incremental research toward solving major, high-risk problems. This focus on creating significant societal impact, rather than just publishing, serves as the direct catalyst for founding ambitious companies like Vivtex.

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D. thumbnail

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago