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To achieve breakthrough work, leaders must embrace spectacular failure. A mediocre "6 out of 10" idea is worse than a "1 out of 10" born from an ambitious attempt at a "10." Mediocrity signals a culture of playing it safe, which kills innovation.

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Effective leadership in an innovation-driven company isn't about being 'tough' but 'demanding' of high standards. The Novonesis CEO couples this with an explicit acceptance of failure as an inherent part of R&D, stressing the need to 'fail fast' and learn from it.

Innovation requires moving beyond a 'failure culture' to an 'anti-fragility' mindset. This means proactively pushing boundaries with the expectation that a percentage of work will fail, then using that failure to fundamentally adjust your thinking and become stronger.

True innovation requires leaders to adopt a venture capital mindset, accepting that roughly nine out of ten initiatives will fail. This high tolerance for failure, mirroring professional investment odds, is a prerequisite for the psychological safety needed for breakthrough results.

Much like a failed surgery provides crucial data for a future successful one, business failures should be seen as necessary steps toward a breakthrough. A "scar" from a failed project is evidence of progress and learning, not something to be hidden. This mindset is foundational for psychological safety.

Top performers intentionally push themselves to their "danger line"—the messy edge of their capabilities where breakthroughs and failures are equally possible. This uncomfortable state of risk is required to unlock potential, yet most people actively avoid it in their personal and professional lives.

Leaders like LinkedIn's Reid Hoffman and Netflix's Reid Hastings view a lack of failure not as perfection, but as a red flag for insufficient risk-taking and slow progress. They believe making mistakes is a necessary byproduct of innovation and achieving ambitious goals.

Setting exceptionally high goals is critical for outlier success. Even falling short of a massive ambition will produce a better outcome than succeeding at a modest one. The process of striving for greatness generates significant value, regardless of the final result.

The most successful people, from Nobel laureates to elite athletes, fail more often than their peers. Their success is a direct result of their willingness to take smart risks and push boundaries, knowing failure is a possible outcome. They adopt a mindset of playing to win rather than the more defensive posture of playing not to lose.

To foster an innovative team that takes big swings, leaders must create a culture of psychological safety. Team members must know they won't be fired for a failed experiment. Instead, failures should be treated as learning opportunities, encouraging them to be edgier and push boundaries.

To foster psychological safety for innovation, leaders must publicly celebrate the effort and learning from failed projects, not just successful outcomes. Putting a team on a pedestal for a six-month project that didn't ship sends a stronger signal than any monetary award.