Unlike a nuclear attack, for which there is no public protection plan, a detailed biological war survival plan exists. However, it is designed exclusively to ensure continuity of government by protecting a small, pre-selected group of officials, not the general population.

The idea that AI is required to create a catastrophic biological weapon is false. The Soviet Union's Biopreparat program successfully produced and stockpiled transmissible viruses like smallpox in large quantities for strategic use, demonstrating that this capability has existed for decades.

A malevolent actor using a published list of deadly viruses could release multiple pathogens at once from many locations. This would overwhelm medical systems and, most critically, cause societal collapse when essential frontline workers refuse to risk their lives and families for their jobs, shutting down the supply of food, power, and law enforcement.

During a civilization-collapsing event, the US government activates "Devolution," a classified continuity plan. A pre-selected group of officials with "go bags" are evacuated to secure, undisclosed facilities to ensure the government continues to function while the general populace is left to fend for itself.

The Soviet Union's goal with its bioweapons program was not just mass death but also psychological devastation. By engineering pathogens resistant to known cures like antibiotics, they aimed to shatter the American public's faith in its medical establishment, leading to societal collapse.

While nuclear weapons are more destructive, the Department of Defense views biological weapons as a greater overall danger. This is due to their dangerously low barrier to entry, as they can be engineered with minimal training and available tools, bypassing military safeguards.

Stockpiling multi-strain vaccines offers a strategic deterrent. While potentially less effective than a targeted vaccine, they can protect essential workers and military personnel, ensuring society continues to function during an attack. This resilience makes a biological attack a less attractive strategy for an adversary.

The next major biological threat may not be a single event like COVID-19, but rather 'waves and waves of new pandemics.' This is due to the increasing accessibility and decreasing cost of the knowledge and equipment needed to create novel pathogens, potentially allowing individuals to tinker with viruses in their basements, leading to frequent lab leaks.

In high-level war games, the Department of Defense's primary concern shifts quickly from the pathogen itself to the secondary effects of its release. The complete breakdown of civil order, mass anarchy, and armed insurrection are considered the more complex and dangerous long-term national security threats.