For B2B re-engagement, a highly effective subject line is "Are you still with [Company Name]?". This personalizes the email at scale by dynamically inserting the contact's employer. It grabs attention and prompts an open to confirm or update their status, successfully re-engaging them with your content or offers.

From Nov 20th to Dec 20th, sending a personal letter-style email from a founder or executive to unengaged contacts can increase open rates by 40%. The key is changing the "from name" to a person, not the brand, and using a subject line that acknowledges their absence. This strategy works for both B2B and B2C brands.

Personalization is not one-size-fits-all. Director-level and above prospects are 50% more likely to respond to company-level relevance (e.g., business initiatives). In contrast, individual contributors and managers are more receptive to individual-level personalization.

Instead of waiting for customers to churn, use AI to monitor key engagement metrics in real time (e.g., portal logins, link clicks). When a user shows signs of disengagement, trigger a personalized, automated nudge via SMS or email to get them back on track before they are lost.

Combine two specific audience identifiers in your subject line, like role and company attribute ("Mid-market CMOs") or interest and a pain point ("Beauty fans with sensitive skin"). This "double personalization" tactic reportedly increases B2B open rates by 24% and B2C by 29% by making the message feel hyper-relevant.

Focusing on email open rates can lead to clickbait subject lines and weak copy. Instead, orient your entire outreach strategy around getting a reply. This forces you to write more personalized, engaging content that addresses the recipient's specific pain points, leading to actual conversations, not just vanity metrics.

Personalizing subject lines with a recipient's industry or interests is a known tactic that provides a solid 20% lift in open rates. However, this should be considered a baseline, as more advanced psychological tactics like aspirational messaging can yield even higher returns of 24-28%.

Adding a deeply personal postscript (P.S.) to cold emails, such as referencing the recipient's favorite whiskey, demonstrates genuine research and builds rapport. This simple tactic humanizes the outreach and can dramatically increase the likelihood of getting a response from a busy executive.

Instead of randomly contacting a large list of neglected accounts, use modern tools to make an educated guess about where to start. AI can quickly summarize past interactions, identify former buyers who have moved to new companies, or flag potential champions within an organization. This allows for a more strategic and personalized re-engagement effort.