Contrary to the post-COVID trend of tech decentralization, the intense talent and capital requirements of AI have caused a rapid re-centralization. Silicon Valley has 'snapped back' into a hyper-concentrated hub, with nearly all significant Western AI companies originating within a small geographic radius.

The ideal founder archetype starts with deep technical expertise and product sense. They then develop exceptional business and commercial acumen over time, a rarer and more powerful combination than a non-technical founder learning the product.

Growing up in the Midwest instills humility and strong relationship-building skills, assets in venture capital. However, this can translate into a lack of aggression and pushiness, a potential handicap in the hyper-competitive Silicon Valley environment where it can lead to missed opportunities early on.

VCs who spin out of tech giants like Airbnb have a powerful initial network. However, this edge typically expires after their third fund as original colleagues move on, forcing them to build a more durable, independent network to source deals.

Contrary to the remote-first trend, Crisp.ai's founder advises against a fully distributed model for initial product development. He argues for gathering the core team in one physical location to harness the energy and efficiency of in-person collaboration. Distributed teams are better suited for iterating on an already established product.

CZI's Biohub model hinges on a simple principle: physically seating biologists and engineers from different institutions (Stanford, UCSF, Berkeley) together. This direct proximity fosters collaboration and creates hybrid experts, overcoming the institutional silos often reinforced by traditional grant-based funding.

To win highly sought-after deals, growth investors must build relationships years in advance. This involves providing tangible help with hiring, customer introductions, and strategic advice, effectively acting as an investor long before deploying capital.

Raising venture capital is often a network-driven game. If you don't already have a network of VCs or a clear path through an accelerator, your focus should not be on fundraising. Instead, dedicate your effort to building a product people want and gaining traction. VCs will find you once you have something compelling to show.