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  1. Invest Like the Best with Patrick O'Shaughnessy
  2. David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450]
David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450]

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450]

Invest Like the Best with Patrick O'Shaughnessy · Dec 2, 2025

a16z's David George on growth investing, backing 'technical terminators,' the winner-take-all nature of tech, and navigating the AI wave.

Top Founders Are 'Technical Terminators' Who Master Business Skills Later

The ideal founder archetype starts with deep technical expertise and product sense. They then develop exceptional business and commercial acumen over time, a rarer and more powerful combination than a non-technical founder learning the product.

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450] thumbnail

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450]

Invest Like the Best with Patrick O'Shaughnessy·3 months ago

Assume 90% of a New Technology's Economic Surplus Goes to Users, Not Companies

During major platform shifts like AI, it's tempting to project that companies will capture all the value they create. However, competitive forces ensure the vast majority of productivity gains (the "surplus") flows to end-users, not the technology creators.

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450] thumbnail

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450]

Invest Like the Best with Patrick O'Shaughnessy·3 months ago

Win Competitive Growth Deals By Acting Like an Investor for Years Before the Round

To win highly sought-after deals, growth investors must build relationships years in advance. This involves providing tangible help with hiring, customer introductions, and strategic advice, effectively acting as an investor long before deploying capital.

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450] thumbnail

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450]

Invest Like the Best with Patrick O'Shaughnessy·3 months ago

Markets Consistently Underprice Persistent High Growth Because It Is Unnatural to Model

Financial models struggle to project sustained high growth rates (>30% YoY). Analysts naturally revert to the mean, causing them to undervalue companies that defy this and maintain high growth for years, creating an opportunity for investors who spot this persistence.

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450] thumbnail

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450]

Invest Like the Best with Patrick O'Shaughnessy·3 months ago

The Private Tech Market Is a $5 Trillion Asset Class, Not a Niche

Venture-backed private companies represent a massive, $5 trillion market cap, exceeding half the value of the 'Magnificent Seven' public tech stocks. This scale signifies that private markets are now a mature, institutional asset class, not a small corner of finance.

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450] thumbnail

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450]

Invest Like the Best with Patrick O'Shaughnessy·3 months ago

Andreessen Horowitz Rejects Investment Committees for a 'Single Trigger' Partner Model

A16z's growth fund avoids traditional investment committees, which can lead to politicization and slow decisions. Instead, it uses a venture-style "single trigger" model where one partner can champion a deal, encouraging intellectual honesty and speed.

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450] thumbnail

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450]

Invest Like the Best with Patrick O'Shaughnessy·3 months ago

Waymo's Success Shows Consumer Pull Can Justify Investing in Long-Timeline Tech

When investing in high-risk, long-development categories like autonomous vehicles, the key signal is undeniable consumer pull. Once Waymo became the preferred choice in San Francisco, it validated the investment thesis despite a decade of development and high costs.

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450] thumbnail

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450]

Invest Like the Best with Patrick O'Shaughnessy·3 months ago

Most Tech Markets Follow the 'Glengarry Glen Ross' Rule: First Prize Wins, Second Gets Steak Knives

Contrary to the belief that number two players can be viable, most tech markets are winner-take-all. The market leader captures the vast majority of economic value, making investments in second or third-place companies extremely risky.

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450] thumbnail

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450]

Invest Like the Best with Patrick O'Shaughnessy·3 months ago

For AI Startups, Low Gross Margins Are a Badge of Honor Indicating Product Usage

Unlike SaaS, where high gross margins are key, an AI company with very high margins likely isn't seeing significant use of its core AI features. Low margins signal that customers are actively using compute-intensive products, a positive early indicator.

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450] thumbnail

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth - [Invest Like the Best, EP.450]

Invest Like the Best with Patrick O'Shaughnessy·3 months ago