In cases of extreme violence, we seldom investigate underlying biological factors unless there's an obvious "smoking gun" like a brain tumor. The discovery of a rare MAOA gene mutation causing extreme aggression in a Dutch family raises the question of how often people are labeled as "evil" without any search for an organic cause.

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The consistent pattern of men committing mass violence is rooted in biological evolution. Men are wired for aggression and physical confrontation, a trait historically selected for by women seeking protectors. This is a biological reality, not a surprising social anomaly.

Ideologies that rely on a 'blank slate' view of human nature have made a catastrophic error. As genetic technologies become mainstream, the public is forced to confront the tangible reality of genetic predispositions in their own reproductive choices. This will unravel the blank slate worldview, a cornerstone of some progressive thought.

Research shows that the same genetic predispositions for physical aggression (e.g., fighting) in boys can manifest as relational aggression (e.g., social exclusion, reputation damage) in girls. This highlights a common biological root for sex-differentiated expressions of aggression, which can be equally damaging.

The depraved acts of many in Epstein's circle may not stem from a clinical disorder like pedophilia, but from an extreme entitlement born of immense wealth and power. This delusion of being above societal rules is presented as a more insidious and dangerous phenomenon.

Violent acts are not random; they often represent the logical conclusion within a person's specific frame of reference. If an ideology convinces someone they are fighting a Hitler-like evil, then assassination becomes a moral duty, not a crime. The danger lies in these justifying belief systems.

The crisis among young men stems from a societal narrative that pathologizes their core biological impulses. Traits like aggression, dominance, and ambition, which are natural drivers, are now deemed toxic. This creates internal conflict and a sense of worthlessness, contributing to 'deaths of despair.'

Genes linked to addiction, impulsivity, and aggression are most active during fetal development, affecting the brain's fundamental balance of inhibition and excitation. This reframes addiction and conduct disorders as neurodevelopmental conditions akin to ADHD, rather than purely as choices or moral failings.

A powerful experiment showed a rat will stop working to free a trapped peer if it can self-administer heroin instead. This demonstrates how high-dopamine drugs can hijack and override our innate drive for social connection, causing people to deviate from their moral compass and stop caring about others.

The onset of antisocial behavior before age 10 is one of the biggest predictors of a lifelong pattern of offending. Cold, callous aggression towards others or animals at this young age, often with a heavy genetic component, has a poor prognosis and currently has vanishingly few effective treatments.

Your outcomes are influenced not just by your own DNA but by the genes of those in your social environment, a concept called 'genetic nurture.' A spouse’s genes can affect your likelihood of depression, and a child's genes can evoke specific parenting behaviors, showing that the effect of genes doesn't stop at our own skin.

Society Rarely Seeks Biological Causes for Horrific Behavior, Defaulting to Moral Condemnation | RiffOn