One host uploaded his anonymized 23andMe genetic data to ChatGPT, instructing it to act as a specific health expert (Gary Brekka). This allowed him to identify a genetic mutation and a corresponding B12 vitamin deficiency, leading to a significant health improvement, demonstrating a novel use of consumer AI for personalized medicine.
Powerful AI models for biology exist, but the industry lacks a breakthrough user interface—a "ChatGPT for science"—that makes them accessible, trustworthy, and integrated into wet lab scientists' workflows. This adoption and translation problem is the biggest hurdle, not the raw capability of the AI models themselves.
The medical community is slow to adopt advanced preventative tools like genomic sequencing. Change will not come from the top down. Instead, educated and savvy patients demanding these tests from their doctors will be the primary drivers of the necessary revolution in personalized healthcare.
The next evolution in personalized medicine will be interoperability between personal and clinical AIs. A patient's AI, rich with daily context, will interface with their doctor's AI, trained on clinical data, to create a shared understanding before the human consultation begins.
Consolidate your values, goals, and principles into a single document. Upload this "master prompt" to an AI before any query, ensuring all responses are tailored to your unique context. This transforms a generic tool into a personalized advisor that understands you deeply.
The value of a personal AI coach isn't just tracking workouts, but aggregating and interpreting disparate data types—from medical imaging and lab results to wearable data and nutrition plans—that human experts often struggle to connect.
Instead of replacing experts, AI can reformat their advice. It can take a doctor's diagnosis and transform it into a digestible, day-by-day plan tailored to a user's specific goals and timeline, making complex medical guidance easier to follow.
To get higher-quality input from busy medical experts, use specialized AI tools like Consensus.app to review scientific literature first. Then, present your tentative conclusions to the professional, demonstrating you've done the preliminary work, which encourages a more thoughtful and detailed response.
By continuously feeding lab results and treatment updates into GPT-5 Pro, the speaker created an AI companion to validate the medical team's decisions. This not only caught minor discrepancies but, more importantly, provided immense peace of mind that the care being administered was indeed state-of-the-art.
Generic AI tools provide generic results. To make an AI agent truly useful, actively customize it by feeding it your personal information, customer data, and writing style. This training transforms it from a simple tool into a powerful, personalized assistant that understands your specific context and needs.
A major frustration in genetics is finding 'variants of unknown significance' (VUS)—genetic anomalies with no known effect. AI models promise to simulate the impact of these unique variants on cellular function, moving medicine from reactive diagnostics to truly personalized, predictive health.