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Dave Morin highlights portfolio company Pulsia as a model for the next wave of AI startups. It provides an agent orchestration system that enables others to build their own agent-based businesses, acting like a "Shopify for the agentic world" by handling everything from market research to ad buying.

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VCs traditionally advise against early product expansion. But with agentic AI, which leverages existing metadata to solve new problems without building new screens, startups can rapidly add capabilities to meet customer demand for a single, unified agent, accelerating the compound startup model.

Platforms like Nebula allow founders to move beyond simple automation. By providing a high-level directive and connecting services, AI agents can run entire business functions, like a content blog that researches, writes, and publishes daily with minimal human intervention.

Pulsia represents a new paradigm where AI doesn't just assist users but autonomously runs their businesses. It wakes up daily to perform tasks like coding, marketing, and ad management. This "company-in-a-box" model, with a subscription plus revenue share, makes entrepreneurship more accessible.

Joe Lonsdale advises established SaaS companies to go on offense with AI. Instead of merely defending their core product, they should build AI agents on top of their platforms to automate customer workflows. This creates new, high-margin revenue streams by helping customers reduce headcount and increase efficiency.

The business model is shifting from selling software to selling outcomes. Instead of creating a tool and inviting users, create pre-trained agents that perform valuable work. Then, invite companies to a workspace where this 'team' of AI employees is ready to start delivering value immediately.

Simply adding a generative AI co-pilot is now table stakes for SaaS companies. The founder argues the next evolution is 'agentic AI' — systems that don't just provide insights but autonomously perform tasks and make decisions for the user, like qualifying and actioning a sales lead.

A company called Pulsia, run by a sole founder, is using AI agents to operate and grow its business, reportedly jumping from $100k to $700k ARR in a week. This points to a future of highly automated, capital-efficient companies that may not require traditional VC.

A new model for entrepreneurship is emerging where solo founders use a suite of AI agents to fulfill roles traditionally held by human co-founders. This 'digital co-founder' approach can handle diverse business functions, enabling rapid and lean startup creation by a single person.

Similar to how mobile gave rise to the App Store, AI platforms like OpenAI and Perplexity will create their own ecosystems for discovering and using services. The next wave of winning startups will be those built to distribute through these new agent-based channels, while incumbents may be slow to adapt.

The true advantage for new AI-native companies lies not in simply using AI tools, but in building entirely new business models around them. This mirrors how Direct-to-Consumer brands leveraged Shopify not just to sell online, but to fundamentally change distribution, marketing, and customer relationships, thereby outmaneuvering incumbents.