AI agents are proving highly effective at reactivating cold leads that human salespeople deem not worth their time. SaaStr founder Jason Lemkin shared an example of an AI agent closing a $100,000 deal on a Saturday night by tirelessly following up with an old, scored lead that his human team had given up on.
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Don't just replace human tasks with AI. Deploy AI agents to handle leads your sales team ignores, like small deals or low-scored prospects. This untapped segment, as SaaStr found with a 15% ticket revenue lift, represents significant growth potential by filling a gap in your GTM process that humans create themselves.
Instead of replacing top performers, AI should be used to do work humans physically cannot. Salesforce targeted a backlog of 100 million 'orphan leads,' using an AI agent to work through 8,000 dormant leads in three weeks. This generated $500,000 in pipeline that would have otherwise been zero.
The most immediate ROI for AI sales agents is not replacing existing salespeople, but engaging the long tail of low-value leads or free trial users in a PLG motion. This "AI-Led Growth" creates a business model where none existed before.
Simple AI's success highlights a key AI advantage in sales. Unlike human agents who may feel uncomfortable, forget, or get discouraged by rejection, the AI consistently and politely pursues upsells, leading to significantly higher revenue potential.
The most effective use of AI in sales is not to replace core selling activities but to handle low-value 'grunt work' like research, list building, and follow-ups. This strategy frees up a salesperson's time to focus on irreplaceable human skills like listening, building trust, and navigating complex emotions.
Don't just "turn on" an AI sales agent and expect results. The only path to success is to first identify what works with your human reps—the scripts, the process, the data. Then, you must manually train the AI on that proven playbook, iterating and refining its performance daily for at least a month. The AI automates success; it doesn't create it from scratch.
Jason Lemkin's company, SaaStr, transitioned from a go-to-market team of roughly 10 humans to just 1.2 humans managing 20 AI agents. This new, AI-driven team is achieving the same level of business performance as the previous all-human team, demonstrating a viable new model for sales organizations.
A powerful, untapped use case for AI is reviving neglected leads directly within your CRM. An agent native to Salesforce can access all historical data to send highly personalized follow-ups to thousands of leads your team previously ghosted, effectively turning forgotten data into new opportunities.
Clogging a sales calendar with unqualified prospects is a major bottleneck. Deploy an AI voice agent to call new leads and ask a single, ruthless qualifying question. This immediately filters out bad fits, freeing up sales reps to focus only on high-probability deals.
By building a custom AI agent for inbound lead qualification, Vercel reduced its inbound SDR team from ten people to one. The agent, which cost only $1,000 per year to run, maintained conversion rates while decreasing response time and number of touches needed.
