Resolution Therapeutics' CEO builds his team with leaders from varied backgrounds across different diseases and drug modalities. He believes this diversity creates more robust problem-solving, as challenges that are novel in one area may have been solved in another, enabling faster and more informed decisions.
When hiring for multiple roles at once, evaluators naturally consider the diversity of the group as a whole. This 'set' mindset encourages a mix of backgrounds and skills. In contrast, hiring one-off candidates leads to focusing on individual fit without considering the broader team composition, often reducing diversity.
True innovation stems from cognitive and interest diversity. Pairing passionate people from disparate fields—like AI and cheese—sparks more creative conversations and breakthroughs than grouping people with similar interests, which merely creates an echo chamber.
Recursion's CEO Najat Khan argues that the key to success in tech-bio is not just hiring scientists and engineers, but cultivating a 'bilingual' culture. This requires scientists who understand AI's limitations and AI experts who appreciate the humility needed for science. This integrated talent and culture is a core competitive advantage that is difficult for larger, more siloed organizations to replicate.
The most effective masterminds consist of people from different industries and business stages. This diversity prevents direct comparison and fosters richer insights. The crucial factor for curation isn't similar resumes but shared values like generosity, honesty, and a willingness to learn. Energy alignment trumps expertise alignment.
Scientists in specialized roles like immunogenicity risk becoming siloed service providers. To maintain impact and growth, they must proactively collaborate with other functions like CMC, safety, and quality. This provides a holistic view of drug development and integrates their expertise into the entire process.
Hiring for "cultural fit" can lead to homogenous teams and groupthink. Instead, leaders should seek a "cultural complement"—candidates who align with core values but bring different perspectives and experiences, creating a richer and more innovative team alchemy.
Instead of hiring designers with similar profiles for easier staffing, intentionally seek out diverse skill sets that fill existing gaps. This leads to more interesting collaboration, broader capabilities, and mutual respect within the team.
Don't default to hiring people who have "done the job before," even at another startup. Unconventional hires from different backgrounds (e.g., archaeologists in customer success) can create unique creativity. The priority should be finding the right fit for your company's specific stage and needs, not just checking an experience box.
Kenai CEO Nick Manusos attributes his startup success to his varied background at Abbott Labs, moving from manufacturing to sales to BD. This breadth prepared him to handle the multifaceted demands of a startup, where a leader must be a generalist who is comfortable with constant change.
The most important job of a leader is team building. This means deliberately hiring functional experts who are better than the CEO in their specific fields. A company's success is a direct reflection of the team's collective talent, not the CEO's individual brilliance.