Many cancer cells rely heavily on glucose (the Warburg effect) and cannot efficiently use ketones. A strict ketogenic diet may starve these tumors while nourishing healthy cells. In one case, it led to a 70% reduction in cancer markers in six weeks, far exceeding chemotherapy's expected 30%.

In its rush for the next breakthrough, the field of psychiatry often discards older, effective treatments due to historical stigma. For instance, MAO inhibitors and modern, safer Electroconvulsive Therapy (ECT) are highly effective for specific depression types but are underutilized because of past negative associations, a phenomenon driven more by politics than science.

Dr. Fred Hatfield, a famous powerlifter, reportedly achieved years of remission from metastatic prostate cancer by implementing a 'sardine fast.' This protocol involved consuming only one can of sardines per day for one week each month, similar to a fasting-mimicking diet.

Wet lab experiments are slow and expensive, forcing scientists to pursue safer, incremental hypotheses. AI models can computationally test riskier, 'home run' ideas before committing lab resources. This de-risking makes scientists less hesitant to explore breakthrough concepts that could accelerate the field.

The NIH's cancellation of mRNA research is a profound strategic error. The technology's key advantage is speed, which is critical not only for future pandemics but also for personalized cancer treatments. These therapies must be developed for individual patients quickly, making mRNA the most promising platform.

Building the first large-scale biological datasets, like the Human Cell Atlas, is a decade-long, expensive slog. However, this foundational work creates tools and knowledge that enable subsequent, larger-scale projects to be completed exponentially faster and cheaper, proving a non-linear path to discovery.

Regulating technology based on anticipating *potential* future harms, rather than known ones, is a dangerous path. This 'precautionary principle,' common in Europe, stifles breakthrough innovation. If applied historically, it would have blocked transformative technologies like the automobile or even nuclear power, which has a better safety record than oil.

Luckey's invention method involves researching historical concepts discarded because enabling technology was inadequate. With modern advancements, these old ideas become powerful breakthroughs. The Oculus Rift's success stemmed from applying modern GPUs to a 1980s NASA technique that was previously too computationally expensive.

A 7-year study of healthy individuals over 85 found minimal genetic differences from their less healthy counterparts. The key to their extreme healthspan appears to be a robust immune system, which is significantly shaped by lifestyle choices, challenging the common narrative about being born with "good genes."