The creation of OpenFold was driven by former academics in industry who missed the collaborative models of academia. They saw that replicating DeepMind's restricted AlphaFold tool individually was a massive waste of resources and sought to re-establish a shared, open-source approach for foundational technologies.

OpenFold's strategy isn't just to provide a free tool. By releasing its training code and data, it enables companies to create specialized versions by privately fine-tuning the model on their own proprietary data. This allows firms to maintain a competitive edge while leveraging a shared, open foundation.

Simply offering the latest model is no longer a competitive advantage. True value is created in the system built around the model—the system prompts, tools, and overall scaffolding. This 'harness' is what optimizes a model's performance for specific tasks and delivers a superior user experience.

Creating frontier AI models is incredibly expensive, yet their value depreciates rapidly as they are quickly copied or replicated by lower-cost open-source alternatives. This forces model providers to evolve into more defensible application companies to survive.

While US firms lead in cutting-edge AI, the impressive quality of open-source models from China is compressing the market. As these free models improve, more tasks become "good enough" for open source, creating significant pricing pressure on premium, closed-source foundation models from companies like OpenAI and Google.

The current trend toward closed, proprietary AI systems is a misguided and ultimately ineffective strategy. Ideas and talent circulate regardless of corporate walls. True, defensible innovation is fostered by openness and the rapid exchange of research, not by secrecy.

To avoid a future where a few companies control AI and hold society hostage, the underlying intelligence layer must be commoditized. This prevents "landlords" of proprietary models from extracting rent and ensures broader access and competition.

The idea that one company will achieve AGI and dominate is challenged by current trends. The proliferation of powerful, specialized open-source models from global players suggests a future where AI technology is diverse and dispersed, not hoarded by a single entity.

Contrary to fears of displacement, AI tools like 'AI co-scientists' amplify human ingenuity. By solving foundational problems (like protein folding) and automating tedious tasks, AI enables more researchers, even junior ones, to tackle more complex, high-level scientific challenges, accelerating discovery.