Many cancer cells rely heavily on glucose (the Warburg effect) and cannot efficiently use ketones. A strict ketogenic diet may starve these tumors while nourishing healthy cells. In one case, it led to a 70% reduction in cancer markers in six weeks, far exceeding chemotherapy's expected 30%.

The entire lining of your gut—a critical barrier protecting your immune system—completely regenerates every three to five days. This incredibly fast turnover means positive dietary changes can have a near-immediate impact on healing the gut, strengthening immunity, and reducing inflammation.

The goal of fiber is to feed gut bacteria that produce butyrate, a key acid for gut health. However, you can bypass this. Being in a ketogenic state directly provides beta-hydroxybutyrate (a ketone) to the gut, strengthening the microbiome without requiring high fiber intake.

Beyond being an alternative fuel source, the ketone body beta-hydroxybutyrate (BHB) functions as a signaling molecule. It acts as an HDAC inhibitor, which can activate genes that enhance the body's antioxidant and cellular defense mechanisms, a pathway of interest in cancer therapy.

In a head-to-head study, a diet high in fermented foods like yogurt and kimchi significantly increased microbiome diversity and lowered markers of inflammation. A high-fiber diet did not consistently produce these effects, suggesting that introducing live microbes is a more direct strategy for improving gut health and immune status in Western populations.

Transferring a healthy person's stool can shut down severe infections like C. diff almost overnight. This procedure is a powerful alternative to major surgery or failed antibiotic treatments, showcasing the gut microbiome's critical role in immune function.

A common multiple myeloma treatment, autologous stem cell transplant, causes a significant decrease in beneficial, butyrate-producing gut bacteria. This treatment-induced change is directly associated with inferior progression-free survival, revealing a paradoxical negative effect of a standard therapy.

A healthy gut is crucial for a strong immune response to cancer. In studies on melanoma patients, administering a fecal transplant from a donor who responded well to immunotherapy literally doubled the number of recipients who successfully beat their cancer, showing a direct gut-cancer treatment link.

Increasing fiber intake may not improve gut health if an individual's microbiome is already depleted. Research suggests many people in the industrialized world have lost the specific microbes needed to break down diverse fibers. Without these microbes, the fiber passes through without providing benefits, highlighting the need to first restore microbial diversity.