By negotiating prices down from over $1,000 to as low as $150 per month, the government deal fundamentally shifts Ozempic's market position. It is no longer a high-end luxury akin to plastic surgery but an accessible wellness product comparable to a fancy gym membership, dramatically expanding its addressable market.

A key expansion strategy is moving 'upper funnel' from treating specific, acute conditions to offering a holistic, preventative platform. For Hims & Hers, adding diagnostics ('Labs') created a new entry point for users to understand their overall health, not just solve one problem.

While digital advertising constitutes 75% of spend in the general economy, it's only about half that in healthcare. This lag, driven by an entrenched reliance on in-person sales reps, creates a long-term secular tailwind for platforms like Doximity as the industry inevitably shifts its marketing budget online.

In regulated spaces like healthcare, product managers must move beyond surface-level collaboration. They need to develop deep domain knowledge and partner with clinicians who are embedded in the product process, co-writing requirements and ideating on solutions, not just acting as consultants.

Unlike incumbents, new biotech and pharma companies often lack established sales forces. They launch with a 'digital first' go-to-market strategy, turning to platforms like Doximity early in their lifecycle. This creates a new and rapidly growing customer segment for Doximity, independent of the incumbents' slower transition.

Doximity integrates multiple workflow tools like telehealth and e-signatures. While specialized competitors might offer better individual products, Doximity wins by providing a convenient, all-in-one platform that doctors are already engaged with daily, creating a powerful defensive moat.

A competitive moat can be built by moving beyond simple service delivery (e.g., shipping medicine) to a closed-loop system. This involves diagnostics to establish a baseline, personalized treatment plans based on results, and ongoing re-testing to demonstrate improvement, creating a sticky user journey.

In emerging but legally ambiguous markets like peptides, the winning strategy may not be selling the product directly. Instead, build the most trusted information source. This creates a high-value audience and positions you to become the top affiliate or a legitimate distributor (like Coinbase in crypto) once regulations clarify.

The future of biotech moves beyond single drugs. It lies in integrated systems where the 'platform is the product.' This model combines diagnostics, AI, and manufacturing to deliver personalized therapies like cancer vaccines. It breaks the traditional drug development paradigm by creating a generative, pan-indication capability rather than a single molecule.