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  1. How I Built This with Guy Raz
  2. Advice Line with Serial Entrepreneur Mark Cuban
Advice Line with Serial Entrepreneur Mark Cuban

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz · Jan 29, 2026

Mark Cuban advises startups to prioritize profit over sales, leverage personal stories for branding, and master supply chain before scaling.

AI Is the Ultimate Democratizer for Aspiring Entrepreneurs

Mark Cuban believes AI is the most dramatic technological shift for entrepreneurs. By providing universal access to knowledge, it levels the playing field and satisfies the crucial entrepreneurial trait of intense curiosity.

Advice Line with Serial Entrepreneur Mark Cuban thumbnail

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz·21 days ago

For Youth Products, Market Fear to Parents, Not Fun to Kids

When selling to teens where parents are the buyers, the core marketing message should be fear-based education for parents. Highlight the dangers of alternatives to create an imperative for them to purchase your safer product.

Advice Line with Serial Entrepreneur Mark Cuban thumbnail

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz·21 days ago

Startups Fail By Chasing Sales Over Margin Dollars and Profits

Mark Cuban warns that the biggest mistake startups make is prioritizing revenue growth over profitability. Chasing sales often leads to burning cash on stocking fees and advertising, jeopardizing long-term survival.

Advice Line with Serial Entrepreneur Mark Cuban thumbnail

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz·21 days ago

Securing Big Box Retail Placement Is a Common Trap for Young Brands

Getting into retailers like Target or Walmart feels like validation, but it can bankrupt startups. The high costs, stocking fees, and immense pressure for sell-through often drain resources and lead to failure.

Advice Line with Serial Entrepreneur Mark Cuban thumbnail

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz·21 days ago

Artisan Brands Should Sell the Creator, Not Just the Product

Mark Cuban advises a craftsman to stop marketing the product brand and start selling the artist's name. The creator's story and skill are the true value, which justifies premium pricing and builds a stronger brand.

Advice Line with Serial Entrepreneur Mark Cuban thumbnail

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz·21 days ago

Artisans Can Earn Free Media by Pitching Live, On-Air Product Creations

Instead of buying ads, craftsmen should pitch local TV shows with an offer to create their product live on air. This provides engaging content for the program and powerful, free promotion for the artisan's brand.

Advice Line with Serial Entrepreneur Mark Cuban thumbnail

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz·21 days ago

Unprofitable Seasonal Brands Should Optimize Supply Chains, Not Add New Products

For a seasonal business not yet profitable, the urge is to add off-season products. Mark Cuban advises against this, urging founders to use downtime to aggressively optimize supply chains and achieve core profitability first.

Advice Line with Serial Entrepreneur Mark Cuban thumbnail

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz·21 days ago

FDA Application Fees, Not Manufacturing Costs, Hinder US Generic Drug Production

Mark Cuban reveals the primary barrier to making generic drugs in the US isn't production cost, which can be cheaper than overseas, but the prohibitive FDA application fees costing hundreds of thousands per drug.

Advice Line with Serial Entrepreneur Mark Cuban thumbnail

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz·21 days ago

Leverage Competing AI Models like ChatGPT and Gemini to Uncover Supply Chain Options

For supply chain research, Mark Cuban suggests querying multiple AI models (ChatGPT, Gemini, etc.) with detailed product and margin data. Comparing their outputs can reveal new manufacturers and cost-saving strategies.

Advice Line with Serial Entrepreneur Mark Cuban thumbnail

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz·21 days ago

Mark Cuban's 'Start Over' Plan: Bartend for Cash Flow, Sell for Long-Term Growth

If he lost everything, Mark Cuban's strategy would be to bartend at night for immediate cash (tips) and work a sales job during the day to build a sustainable career, leveraging his core skills.

Advice Line with Serial Entrepreneur Mark Cuban thumbnail

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz·21 days ago

Mark Cuban's Legacy Goal: Be Known for Fixing Healthcare, Not for Wealth

Cuban's motivation for his company Cost Plus Drugs isn't profit; he'd be happy breaking even. His goal is to fix a universally broken system, driven by competitive spirit and a desire for a legacy beyond wealth.

Advice Line with Serial Entrepreneur Mark Cuban thumbnail

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz·21 days ago

VCs Push for High-Growth Exits; Founders Must Protect Company Control

Mark Cuban highlights the conflict for founders with VC funding: VCs need rapid growth for an exit, which can force founders into risky decisions that dilute equity below 50% and risk the company's long-term health.

Advice Line with Serial Entrepreneur Mark Cuban thumbnail

Advice Line with Serial Entrepreneur Mark Cuban

How I Built This with Guy Raz·21 days ago