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  1. Running Through Walls
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Data-Driven Science and Leadership

Data-Driven Science and Leadership

Running Through Walls · Jan 8, 2026

Tubulus CEO Dominic Schumacher on building next-gen cancer therapies (ADCs) with novel chemistry and leading with a data-driven, trust-based culture.

Scientist CEOs Excel by Applying Data-Driven Rationality to Business

A scientific background can be a major asset in a CEO role, not a liability. The core principles of science—making data-driven, rational, and unemotional decisions—translate directly to the business world. This allows for objective choices that align scientific development with the company's business needs.

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Data-Driven Science and Leadership

Running Through Walls·3 months ago

Scientist-Founders Grossly Underestimate the Time Sink of Active Leadership

Founders transitioning from the lab to a CEO role often misjudge the immense time commitment required for leadership. Building a cohesive team culture, especially across multiple locations, demands significant, active effort, including prioritizing in-person meetings to establish trust and shared values.

Data-Driven Science and Leadership thumbnail

Data-Driven Science and Leadership

Running Through Walls·3 months ago

Biotech Founders Need 'Healthy Naivety' to Overcome Early Obstacles

Tubulus co-founders decided to launch their company after a single successful experiment, driven by passion rather than a thorough market analysis. This 'healthy naivety' helped them push forward despite industry skepticism towards their antibody-drug conjugate (ADC) technology at the time, which was considered a difficult area.

Data-Driven Science and Leadership thumbnail

Data-Driven Science and Leadership

Running Through Walls·3 months ago

Founders Must Believe They'd Bet Their Entire Net Worth to Secure an Anchor Investor

During a tough fundraising process, founders should remove emotion and ask themselves a critical question: 'Would I invest my entire personal fortune into this right now?' Answering 'yes' with rational conviction is the key to weathering rejections and ultimately persuading an anchor investor to make the first bet.

Data-Driven Science and Leadership thumbnail

Data-Driven Science and Leadership

Running Through Walls·3 months ago

A High-Trust Culture Allows a Biotech Startup to Pivot Strategy Overnight

When Tubulus pivoted its lead program from liquid to solid tumors, the team's ability to change direction instantly stemmed directly from the company's foundational culture of trust. Openly explaining the rationale behind major strategic decisions allows employees to follow and execute without friction, even on a dime.

Data-Driven Science and Leadership thumbnail

Data-Driven Science and Leadership

Running Through Walls·3 months ago