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  1. The Marie Forleo Podcast
  2. 469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You
469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You

The Marie Forleo Podcast · Dec 16, 2025

Menopause is a profound brain remodel, not just a hormonal decline. This challenging transition is a chance to shed old identities & find your truth.

Midlife Breakdowns Are a 'Tiramisu of Stress,' Not a Single Event

The feeling of breaking down in midlife isn't caused by a single trigger. It is a cumulative effect of layered stressors—family, career, aging parents, health—that coincide with a period of low biological resilience and high emotional reactivity, creating a 'tiramisu of stress.'

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You thumbnail

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You

The Marie Forleo Podcast·2 months ago

The Grandmother Hypothesis Reframes Menopause as an Evolutionary Upgrade for Leadership

The Grandmother Hypothesis suggests menopause is an evolutionary advantage. Post-menopausal women were critical to tribal survival by providing food and protection. This required a brain rewired for leadership, intuition, and heightened sensitivity to threats, providing a powerful purpose for this life stage.

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You thumbnail

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You

The Marie Forleo Podcast·2 months ago

Publicly Admitting 'I'm Not Okay' Is the First Step to Healing for High-Achievers

For individuals, particularly high-achieving women, who are the 'glue' in their communities, the most powerful step toward healing is admitting they are not okay. This act dismantles performative pressure and creates space for authentic recovery, often revealing a shared struggle among peers.

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You thumbnail

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You

The Marie Forleo Podcast·2 months ago

Menopause Dissolves Your 'Neurochemical Armor,' Forcing a Redefinition of Self

During menopause, the decline of estrogen also means losing its 'girl gang' of neurochemicals (dopamine, serotonin, etc.). This dissolves a lifelong 'neurochemical armor' that fueled motivation and joy, forcing you to redefine your identity and priorities without those chemical drivers.

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You thumbnail

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You

The Marie Forleo Podcast·2 months ago

Menopause Triggers a Brain Remodel, Pruning People-Pleasing Neurons for Leadership

Menopause isn't just a hormonal decline; it's a neurological renovation. The brain actively prunes pathways that supported relational, people-pleasing behaviors and builds new ones for a more independent mindset geared toward leadership. Difficult symptoms are the messy 'remodel' phase.

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You thumbnail

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You

The Marie Forleo Podcast·2 months ago

Fight Menopausal Apathy by Introducing Novelty to Re-stimulate Dopamine

The emotional flatness and lack of motivation common in menopause stems from a drop in dopamine. Instead of forcing yourself through old routines, you can strategically counteract this by introducing novelty. Learning a new sport or changing daily habits helps naturally boost dopamine and reignite drive.

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You thumbnail

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You

The Marie Forleo Podcast·2 months ago

Midlife Transformation Feels Like an Allergic Reaction to Your Former Life

A key sign of a deep midlife identity shift is feeling 'allergic' to passions, routines, and roles you once loved. This isn't a failure but an indicator that you've completed a chapter—'mission accomplished'—and are like a plant that has outgrown its container, ready for something new.

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You thumbnail

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You

The Marie Forleo Podcast·2 months ago

We Celebrate the Butterfly But Ignore the Painful 'Goo Phase' of Transformation

Life transitions like menopause involve a difficult liminal space—the 'goo phase'—where the old identity has dissolved before the new one emerges. Society focuses on the end result (the butterfly) but fails to talk about or support individuals during the disorienting, messy process of becoming 'goo.'

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You thumbnail

469 - Perimenopause Brain Fog & Fatigue? What Doctors Aren't Telling You

The Marie Forleo Podcast·2 months ago