Livestock are fattened with B vitamins to increase their metabolic efficiency, yielding more weight from less feed. For human weight loss, metabolic *inefficiency* is desirable. The widespread fortification of foods with B vitamins may inadvertently make our bodies better at storing calories as fat.

Calorie restriction alone is unsustainable because high-carb meals spike insulin, which sequesters energy from the blood into storage cells. The brain, which lacks storage capacity, perceives this drop in available energy as a crisis and triggers intense, overriding hunger, even if body fat is abundant.

Your body doesn't differentiate between the source of sugar molecules. Sugar from honey, agave, or freshly squeezed juice is processed the same way as sugar from a soda, leading to similar glucose spikes and health impacts. The 'natural' label is irrelevant to the biochemistry.

Many clinicians mistakenly believe insulin's main role is blood glucose control. In reality, it's a master hormone signaling every cell—from brain to bone—to store energy. This function is so powerful it can slow the body's overall metabolic rate to prioritize energy storage.

Our ancestors were healthy by default because their environment promoted it. Today, the default environment—filled with processed foods, sedentary lifestyles, and novel chemicals—systematically produces unhealthy people, making good health an uphill battle of individual effort against the system.

Many chronic illnesses, including high blood pressure, cancer, and cognitive decline, are not separate issues but symptoms of a single underlying problem: chronically elevated insulin levels. This metabolic “trash” accumulates over years, making the body a breeding ground for disease.

The key to understanding modern nutrition is to recognize that all carbohydrates are processed by the body into blood sugar. This mental model—that a loaf of bread is functionally a loaf of sugar—cuts through complex dietary advice and explains why high-carb diets contribute to metabolic diseases.

The vascular damage from sugar is direct and chemical. Excess glucose acts like glue, binding to and disabling the very enzymes that produce nitric oxide. This shuts down the body's ability to dilate blood vessels, leading to a cascade of health issues like hypertension and peripheral neuropathy.

Eating high-carb foods frequently, even in a calorie deficit, keeps insulin high. This prevents your body from accessing stored fat for energy, forcing it to lower its metabolic rate. After the diet, this suppressed metabolism causes rapid weight regain.