Wet lab experiments are slow and expensive, forcing scientists to pursue safer, incremental hypotheses. AI models can computationally test riskier, 'home run' ideas before committing lab resources. This de-risking makes scientists less hesitant to explore breakthrough concepts that could accelerate the field.

Google is moving beyond AI as a mere analysis tool. The concept of an 'AI co-scientist' envisions AI as an active partner that helps sift through information, generate novel hypotheses, and outline ways to test them. This reframes the human-AI collaboration to fundamentally accelerate the scientific method itself.

Sperm whale vocalizations contain discrete, non-continuous sound patterns analogous to human vowels and even diphthongs. This discreteness is a critical building block for complex language, as it allows for clear, combinable units of meaning (like the difference between "bot" and "beat"). This suggests their communication system is more structured than previously understood.

The next leap in biotech moves beyond applying AI to existing data. CZI pioneers a model where 'frontier biology' and 'frontier AI' are developed in tandem. Experiments are now designed specifically to generate novel data that will ground and improve future AI models, creating a virtuous feedback loop.

In high-stakes fields like pharma, AI's ability to generate more ideas (e.g., drug targets) is less valuable than its ability to aid in decision-making. Physical constraints on experimentation mean you can't test everything. The real need is for tools that help humans evaluate, prioritize, and gain conviction on a few key bets.

To make genuine scientific breakthroughs, an AI needs to learn the abstract reasoning strategies and mental models of expert scientists. This involves teaching it higher-level concepts, such as thinking in terms of symmetries, a core principle in physics that current models lack.

For AI systems to be adopted in scientific labs, they must be interpretable. Researchers need to understand the 'why' behind an AI's experimental plan to validate and trust the process, making interpretability a more critical feature than raw predictive power.

AI development has evolved to where models can be directed using human-like language. Instead of complex prompt engineering or fine-tuning, developers can provide instructions, documentation, and context in plain English to guide the AI's behavior, democratizing access to sophisticated outcomes.

Current LLMs fail at science because they lack the ability to iterate. True scientific inquiry is a loop: form a hypothesis, conduct an experiment, analyze the result (even if incorrect), and refine. AI needs this same iterative capability with the real world to make genuine discoveries.