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  1. All-In with Chamath, Jason, Sacks & Friedberg
  2. Bryan Johnson: The #1 Longevity Secret You Can Start Doing Today
Bryan Johnson: The #1 Longevity Secret You Can Start Doing Today

Bryan Johnson: The #1 Longevity Secret You Can Start Doing Today

All-In with Chamath, Jason, Sacks & Friedberg · Oct 14, 2025

Biohacker Bryan Johnson reveals the single most important health hack: lower your resting heart rate before bed to optimize sleep and longevity.

Prioritizing Sleep Makes You a Better Founder, Refuting Startup Martyrdom Culture

Biohacker Bryan Johnson directly challenges the "grind culture" belief that founders must sacrifice health and sleep for success. He argues this is a false narrative, stating that prioritizing high-quality sleep will make an individual a more effective leader, parent, and partner.

Bryan Johnson: The #1 Longevity Secret You Can Start Doing Today thumbnail

Bryan Johnson: The #1 Longevity Secret You Can Start Doing Today

All-In with Chamath, Jason, Sacks & Friedberg·4 months ago

Your Organs Have Different Ages; Target Them Individually to Slow Overall Aging

Bryan Johnson's protocol is based on the concept that each organ ages at its own rate. Identifying an organ's accelerated biological age—like his "64-year-old ear"—allows for targeted interventions that can slow overall aging and prevent related issues like cognitive decline.

Bryan Johnson: The #1 Longevity Secret You Can Start Doing Today thumbnail

Bryan Johnson: The #1 Longevity Secret You Can Start Doing Today

All-In with Chamath, Jason, Sacks & Friedberg·4 months ago

Lower Your Pre-Sleep Heart Rate by 10% to Boost Willpower and Mental Health

Bryan Johnson suggests focusing on a single metric: pre-sleep resting heart rate. Lowering it through specific habits (like eating 4 hours before bed) improves sleep quality, which in turn boosts your prefrontal cortex, enhancing willpower and alleviating mental health issues.

Bryan Johnson: The #1 Longevity Secret You Can Start Doing Today thumbnail

Bryan Johnson: The #1 Longevity Secret You Can Start Doing Today

All-In with Chamath, Jason, Sacks & Friedberg·4 months ago