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  1. OncLive® On Air
  2. S17 Ep72: FDA Approval Insights: Subcutaneous Isatuximab Via an On-Body Delivery System Represents a “Game-Changer” in Multiple Myeloma: With Douglas W. Sborov, MD, MS
S17 Ep72: FDA Approval Insights: Subcutaneous Isatuximab Via an On-Body Delivery System Represents a “Game-Changer” in Multiple Myeloma: With Douglas W. Sborov, MD, MS

S17 Ep72: FDA Approval Insights: Subcutaneous Isatuximab Via an On-Body Delivery System Represents a “Game-Changer” in Multiple Myeloma: With Douglas W. Sborov, MD, MS

OncLive® On Air · Jul 31, 2026

FDA approves subcutaneous isatuximab via an on-body injector for multiple myeloma, a "game-changer" improving patient quality of life and convenience.

On-Body Injector Poised to Shift Isatuximab from Laggard to Leader in Myeloma

Isatuximab previously lagged its competitor, daratumumab, which had a subcutaneous option for years. The new on-body injector (OBI) isn't just about catching up; its efficiency and high patient preference could shift treatment patterns, making it a significant competitive threat and altering its market position.

S17 Ep72: FDA Approval Insights: Subcutaneous Isatuximab Via an On-Body Delivery System Represents a “Game-Changer” in Multiple Myeloma: With Douglas W. Sborov, MD, MS thumbnail

S17 Ep72: FDA Approval Insights: Subcutaneous Isatuximab Via an On-Body Delivery System Represents a “Game-Changer” in Multiple Myeloma: With Douglas W. Sborov, MD, MS

OncLive® On Air·4 days ago

Patient Preference Data Shows On-Body Injectors Outperform Manual Injections

Quantitative data from the ISOLICAL trial reveals an overwhelming patient preference for on-body injectors (OBI) over manual injection. With 75% preferring OBI and 90% choosing it when given an option, patient experience—driven by comfort, reduced pain, and convenience—emerges as a critical factor for technology adoption in oncology.

S17 Ep72: FDA Approval Insights: Subcutaneous Isatuximab Via an On-Body Delivery System Represents a “Game-Changer” in Multiple Myeloma: With Douglas W. Sborov, MD, MS thumbnail

S17 Ep72: FDA Approval Insights: Subcutaneous Isatuximab Via an On-Body Delivery System Represents a “Game-Changer” in Multiple Myeloma: With Douglas W. Sborov, MD, MS

OncLive® On Air·4 days ago

New Drug Delivery Systems Pave the Way for Decentralized Myeloma Cancer Care

The isatuximab on-body injector (OBI) is more than an in-clinic convenience; it represents a key technological step toward moving oncology treatment out of specialized centers. This could enable care closer to or even at patients' homes, particularly benefiting rural patients who face significant travel burdens.

S17 Ep72: FDA Approval Insights: Subcutaneous Isatuximab Via an On-Body Delivery System Represents a “Game-Changer” in Multiple Myeloma: With Douglas W. Sborov, MD, MS thumbnail

S17 Ep72: FDA Approval Insights: Subcutaneous Isatuximab Via an On-Body Delivery System Represents a “Game-Changer” in Multiple Myeloma: With Douglas W. Sborov, MD, MS

OncLive® On Air·4 days ago