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  1. The a16z Show
  2. What It Takes to Build a Startup | Andrew Chen & Matt Perault
What It Takes to Build a Startup | Andrew Chen & Matt Perault

What It Takes to Build a Startup | Andrew Chen & Matt Perault

The a16z Show · Sep 11, 2026

a16z's Andrew Chen discusses "little tech": the 2-3 person startups built at kitchen tables and the unseen regulatory hurdles they face.

a16z's Speedrun Program Aims to Create New Companies, Not Just Fund Them

The accelerator's mission is to get as close as possible to the moment of company creation. It actively encourages founders with full-time jobs to quit by providing the capital and support needed, effectively manufacturing new startups that might have otherwise waited years to launch.

What It Takes to Build a Startup | Andrew Chen & Matt Perault thumbnail

What It Takes to Build a Startup | Andrew Chen & Matt Perault

The a16z Show·23 days ago

A Venture Firm's Reputation Is Built on How It Treats Founders of Failed Startups

While returns come from a small number of breakout companies, a VC firm's long-term reputation and deal flow are determined by its relationship with all founders. How a firm supports founders through failure influences whether they'll back them again or if those founders will recommend the firm to others.

What It Takes to Build a Startup | Andrew Chen & Matt Perault thumbnail

What It Takes to Build a Startup | Andrew Chen & Matt Perault

The a16z Show·23 days ago

Failed Startup Founders Are Valuable Hiring Targets for Other Startups

Rather than being a black mark, leading a failed startup makes a founder highly desirable as an employee. They have proven experience working on unstructured problems, a strong work ethic, and are up-to-date on the latest technology. This makes them prime candidates for roles in other growing companies.

What It Takes to Build a Startup | Andrew Chen & Matt Perault thumbnail

What It Takes to Build a Startup | Andrew Chen & Matt Perault

The a16z Show·23 days ago

Startups Face a Cumulative "Wall" of Regulation, Not Incremental Burdens

Policymakers often debate the incremental impact of a new law. For a new founder, however, the burden is the sum of all existing regulations—privacy, data, employment—which they must comply with simultaneously from inception. This cumulative weight creates massive friction for "little tech."

What It Takes to Build a Startup | Andrew Chen & Matt Perault thumbnail

What It Takes to Build a Startup | Andrew Chen & Matt Perault

The a16z Show·23 days ago

Policymakers Mistake Big Tech's Opinion for an "Industry Consensus" on Regulation

Early-stage founders are focused on survival and don't have lobbyists or time for policy debates. As a result, policymakers primarily hear from large, established tech companies. This creates a skewed view where the perspective of incumbents is often misinterpreted as the consensus for the entire industry.

What It Takes to Build a Startup | Andrew Chen & Matt Perault thumbnail

What It Takes to Build a Startup | Andrew Chen & Matt Perault

The a16z Show·23 days ago

Cities and States Must Compete for Startups; Unfriendly Regulation Will Repel Them

Early-stage startups are highly mobile and can choose where to plant their roots, forcing cities and states into competition. If a region imposes burdensome regulations, such as extra rules on AI, founders will simply choose to build their company in a more favorable environment. Attracting startups is an active choice.

What It Takes to Build a Startup | Andrew Chen & Matt Perault thumbnail

What It Takes to Build a Startup | Andrew Chen & Matt Perault

The a16z Show·23 days ago

Wealth Taxes Can Indirectly Kill Startup Hubs by Driving Away Local Investors

A thriving startup ecosystem requires a dense network of founders, talent, and capital. Policies like a wealth tax, while not directly aimed at startups, can cause angel investors and family offices to move to other geographies. This exodus of capital can starve the local ecosystem, making it less dynamic and powerful.

What It Takes to Build a Startup | Andrew Chen & Matt Perault thumbnail

What It Takes to Build a Startup | Andrew Chen & Matt Perault

The a16z Show·23 days ago

Successful Co-Founder Duos Often Split Roles Into External "Business" and Internal "Product"

A common dynamic observed in two-person founding teams is a natural division of labor. One founder focuses externally on customer interviews and deal-making, while the other focuses internally on building the product and technology. This specialization allows the tiny team to cover critical ground efficiently.

What It Takes to Build a Startup | Andrew Chen & Matt Perault thumbnail

What It Takes to Build a Startup | Andrew Chen & Matt Perault

The a16z Show·23 days ago