As underlying AI models become more capable, the need for complex user interfaces diminishes. The team abandoned feature-rich IDEs like Cursor for Claude Code's simple terminal text box because the model's power now handles the complexity, making a minimal UI more efficient.

Powerful AI models for biology exist, but the industry lacks a breakthrough user interface—a "ChatGPT for science"—that makes them accessible, trustworthy, and integrated into wet lab scientists' workflows. This adoption and translation problem is the biggest hurdle, not the raw capability of the AI models themselves.

Current text-based prompting for AI is a primitive, temporary phase, similar to MS-DOS. The future lies in more intuitive, constrained, and creative interfaces that allow for richer, more visual exploration of a model's latent space, moving beyond just natural language.

Despite access to state-of-the-art models, most ChatGPT users defaulted to older versions. The cognitive load of using a "model picker" and uncertainty about speed/quality trade-offs were bigger barriers than price. Automating this choice is key to driving mass adoption of advanced AI reasoning.

While chatbots are an effective entry point, they are limiting for complex creative tasks. The next wave of AI products will feature specialized user interfaces that combine fine-grained, gesture-based controls for professionals with hands-off automation for simpler tasks.

The best UI for an AI tool is a direct function of the underlying model's power. A more capable model unlocks more autonomous 'form factors.' For example, the sudden rise of CLI agents was only possible once models like Claude 3 became capable enough to reliably handle multi-step tasks.

Open-ended prompts overwhelm new users who don't know what's possible. A better approach is to productize AI into specific features. Use familiar UI like sliders and dropdowns to gather user intent, which then constructs a complex prompt behind the scenes, making powerful AI accessible without requiring prompt engineering skills.

The perceived limits of today's AI are not inherent to the models themselves but to our failure to build the right "agentic scaffold" around them. There's a "model capability overhang" where much more potential can be unlocked with better prompting, context engineering, and tool integrations.

While AI development tools can improve backend efficiency by up to 90%, they often create user interface challenges. AI tends to generate very verbose text that takes up too much space and can break the UX layout, requiring significant time and manual effort to get right.