Japan's biotech ecosystem is evolving with a new, successful model for creating cross-border companies. US venture firms are partnering with Japanese academia, combining American management expertise and capital with Japan's strong science and cost-effective R&D to build globally competitive biotechs from their inception.
China has developed a first-rate biotech effort, enabling U.S. firms to buy or license preclinical assets more efficiently than building them domestically. This creates an arbitrage opportunity, leveraging China's R&D capabilities while relying on U.S. expertise and capital for global commercialization.
Despite representing only 12% of total Asian out-licensing deals, Korean biotechs account for a disproportionately high 20% of "first-in-class" partnerships. This indicates a strong appetite for novel science and high-risk, high-reward innovation, challenging the stereotype of Asian biotech as purely "fast followers."
By partnering with Fujifilm Cellular Dynamics (FCDI), the company that developed its core technology, Kenai avoids a costly and risky tech transfer process. FCDI's existing facility can handle both clinical and future commercial scale-up, a significant operational and financial advantage.
A VC advises Korean entrepreneurs to abandon gradual US entry strategies. The effective model is to "parachute" in—relocating solo to a hub like Boston and immersing oneself in the network. This radical, face-time-centric approach is deemed essential for building the momentum needed for US investment and partnerships.
Successful acquisitions don't just benefit the acquired company's investors. These investors often reinvest their profits into new, earlier-stage ventures, providing crucial capital that fuels the entire biotech ecosystem's growth and innovation.
Faced with China's superior speed and cost in executing known science, the U.S. biotech industry cannot compete by simply iterating faster. Its strategic advantage lies in
Amidst growing uncertainty at the US FDA, biotech companies are using a specific de-risking strategy: conducting early-stage clinical trials in countries like South Korea and Australia. This global approach is not just about cost but a deliberate move to get fast, reliable early clinical data to offset domestic regulatory instability and gain a strategic advantage.
Denmark's leadership in biosolutions is not accidental. It's built on a unique ecosystem combining a cultural heritage in fermentation, patient capital from large foundations like Novo Nordisk, and a dense collaborative network connecting universities and companies of all sizes.
FCDI launched multiple clinical-stage companies (Century, Opsis, Kenai) by providing a proven iPSC technology backbone. This "platform and spinout" model allows new ventures to focus on clinical development rather than early platform discovery, increasing their chances of success and attracting partners.
Contrary to common belief, a BioCentury analysis revealed that two-thirds of out-licensing deals from Asian innovators were with Western biotechs, not large multinational pharmaceutical corporations. This indicates a significant trend of smaller Western companies actively sourcing innovation from Asia.