Founder Taylor Algren's experience as a heart failure patient directly inspired his AI startup, EasyMedicine. This deep personal understanding allows him to build a more human-centric solution for chronic disease patients by authentically anticipating their struggles with the healthcare system.

For early-stage MedTech startups, key milestones for investors are not just regulatory successes. They are fundamental proofs of concept—showing the device works in a model and demonstrating how it would function in a clinical setting. This builds an investor's vision of the product's future.

Zyda raised funds primarily from urologists and urogynecologists. These clinician-investors already understood the market need, provided crucial industry connections (like finding a clinical trial investigator), and became influential early prescribers, dramatically accelerating market entry and validation.

Non-technical founders can attract technical co-founders by first building a manual, non-scalable version of their product. This creates a user base of passionate early adopters who are mission-aligned. The ideal co-founder is often among these first users, as they have already demonstrated belief in the solution.

Successful MedTech innovation starts by identifying a pressing, real-world clinical problem and then developing a solution. This 'problem-first' approach is more effective than creating a technology and searching for an application, a common pitfall for founders with academic backgrounds.

In regulated spaces like healthcare, product managers must move beyond surface-level collaboration. They need to develop deep domain knowledge and partner with clinicians who are embedded in the product process, co-writing requirements and ideating on solutions, not just acting as consultants.

Doximity's product development is 'unapologetically' focused on increasing doctor productivity and saving them time. This user-centric approach builds deep engagement and trust, creating the highly valuable physician audience that forms the foundation of its advertising-based business model.

Technical competence is the easiest part of a technical co-founder to evaluate. The real risks lie in misaligned goals (lifestyle vs. unicorn), personality clashes, and incompatible work styles. Prioritize assessing these crucial "human" factors first.

A crucial piece of advice for biotech founders is to interact with patients as early as possible. This 'patient first' approach helps uncover unmet needs in their treatment journey, providing a more powerful and differentiated perspective than focusing solely on the scientific or commercial landscape.