Society must abandon chronological age as a proxy for ability. People in their 30s can be non-functional, while centenarians can be perfectly functional. The focus should shift to an individual's actual health and capacity, unlocking the potential of older individuals instead of devaluing them based on their birth date.
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Bryan Johnson's protocol is based on the concept that each organ ages at its own rate. Identifying an organ's accelerated biological age—like his "64-year-old ear"—allows for targeted interventions that can slow overall aging and prevent related issues like cognitive decline.
Aging isn't uniform. Your heart might age faster than your brain, predisposing you to cardiovascular disease over Alzheimer's. Quantifying these organ-specific aging rates offers a more precise diagnostic tool than a single 'biological age' and explains why people succumb to different age-related illnesses.
Some individuals possess genetic variants, like FOXO3, that slow their biological clocks. The goal of emerging "gero-protectors" is not immortality but to replicate this advantage for everyone, slowing aging to compress frailty into a shorter period at the end of life and extend healthspan.
Contrary to the ageist view that an older population drains resources, healthy older individuals represent a massive, untapped asset. Their accumulated wisdom, experience, and wealth are a form of "gold" that society must learn to mine by creating opportunities rather than pushing them aside.
Beyond tackling fatal diseases to increase lifespan, a new wave of biotech innovation focuses on "health span"—the period of life lived in high quality. This includes developing treatments for conditions often dismissed as aging, such as frailty, vision loss, and hearing decline, aiming to improve wellbeing in later decades.
A major transformation has occurred in longevity science, particularly in the last eight years. The conversation has moved away from claims of radical life extension towards the more valuable goal of increasing "healthspan"—the period of healthy, functional life. This represents a significant and recent shift in scientific consensus.
Data from the world's longest-lived populations shows the distribution of death is compressing, not shifting to older ages. More people are reaching old age, but the curve is getting tighter, proving a biological wall for average life expectancy around 87 years. This reinforces the need to focus on healthspan.
By auditing the "noise" or corruption in a cell's epigenetic settings, scientists can determine a biological age. This "epigenetic clock" is a better indicator of true health than birth date, revealing that a 40-year-old could have the biology of a 30-year-old.
Contrary to the cultural narrative that aging diminishes relevance, experience brings profound advantages. Older leaders are often smarter, more in tune with their integrity, and less afraid to take risks or disappoint others, making them more effective and resilient.
The common aversion to living to 120 stems from assuming extra years will be spent in poor health. The goal of longevity science is to extend *healthspan*—the period of healthy, mobile life—which reframes the debate from merely adding years to adding high-quality life.