While the sheer number of exoplanets suggests alien life is probable, astrophysicist Sara Seager explains why biologists are skeptical. Since we don't understand the mechanism of how life originated on Earth, we cannot accurately assess the probability of it occurring elsewhere.

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The comet 3I/ATLAS spreads methanol, a building block for life. Loeb posits this could be evidence of panspermia, but takes it further, suggesting it could be a deliberate act. An 'interstellar gardener' with intelligence could be using such objects to seed or experiment with life across the galaxy.

Lee Cronin's Assembly Theory offers a way to find alien life by quantifying molecular complexity. Using mass spectrometry, scientists can search for molecules with a high 'assembly index,' a clear signature that they were constructed by an evolutionary process rather than random chemistry.

The debate over broadcasting messages to aliens is moot. Astrophysicist Sara Seager argues any civilization capable of interstellar travel would first detect the oxygen in our atmosphere—a highly reactive gas that signals life—making our attempts at hiding irrelevant.

The Fermi Paradox—where are the aliens?—can be explained by the "Great Filter" theory. Astrophysicist Alex Filippenko believes this filter is likely in our future, meaning civilizations like ours often destroy themselves before colonizing the galaxy.

Avi Loeb argues that the scientific mainstream has not yet grasped the opportunity presented by interstellar objects. Instead of spending billions of years traveling to other stars, we have materials from them arriving in our 'backyard.' Analyzing these objects is a low-cost way to search for the building blocks of life elsewhere.

Astrophysicist Sara Seager reframes the Fermi Paradox, suggesting advanced civilizations might not contact us for the same reason we don't talk to ants. We are simply not interesting enough to warrant their attention or energy, even if they are studying us from a distance.

Since Mars cooled and had water before Earth, Avi Loeb argues life likely started there first. This primordial life could have been transported to Earth inside rocks ejected by asteroid impacts. This makes humans descendants of Martian microbes and Elon Musk's mission a 'return to our childhood home'.

The reason we don't see aliens (the Fermi Paradox) is not because they are distant, but because our spacetime interface is designed to filter out the overwhelming reality of other conscious agents. The "headset" hides most of reality to make it manageable, meaning the search for physical extraterrestrial life is fundamentally limited.

Intricate mechanisms like the DNA double helix and cellular energy production are identical across all life forms. The sheer complexity makes it statistically impossible for them to have evolved twice, serving as irrefutable evidence that all species descended from one common ancestor.

The search for extraterrestrial life focuses on "chemical disequilibrium." The simultaneous presence of oxygen and methane in an exoplanet's atmosphere would be a strong indicator of life, as they naturally destroy each other, implying a constant biological source is replenishing them.