Companies run numerous disconnected AI pilots in R&D, commercial, and other silos, each with its own metrics. This fragmented approach prevents enterprise-wide impact and disconnects AI investment from C-suite goals like share price or revenue growth. The core problem is strategic, not technical.

The excitement around AI often overshadows its practical business implications. Implementing LLMs involves significant compute costs that scale with usage. Product leaders must analyze the ROI of different models to ensure financial viability before committing to a solution.

Founders are consistently and universally wrong about their financial projections, particularly cash runway. AI tools can provide an objective, data-driven forecast based on trailing growth, correcting for inherent founder optimism and preventing critical miscalculations.

Many firms engage in "innovation theatre," building a portfolio of impressive but isolated AI pilots. Without a unifying strategic architecture connecting them to core growth objectives, these initiatives remain islands that fail to scale, compound, or move overall enterprise performance.

Many pharma companies allow various departments to run numerous, disconnected AI pilots without a central strategy. This lack of strategic alignment means most pilots fail to move beyond the proof-of-concept stage, with 85% yielding no measurable return on investment.

AI requires significant upfront investment with uncertain returns, creating an "investment paradox" for CFOs. Traditional ROI models are insufficient. A new financial framework is needed that measures not just cost savings but also revenue acceleration, risk mitigation, and the strategic option value of competitive positioning.

A traditional IT investment ROI model misses the true value of AI in pharma. A proper methodology must account for operational efficiencies (e.g., time saved in clinical trials, where each day costs millions) and intangible benefits like improved data quality, competitive advantage, and institutional learning.

Pharma companies engaging in 'pilotitis'—running random, unscalable AI projects—are destined to fall behind. Sustainable competitive advantage comes from integrating AI across the entire value chain and connecting it to core business outcomes, not from isolated experiments.

While healthcare companies widely use AI for cost savings and R&D efficiency, it has not yet translated into measurable revenue or earnings growth. For equity investors, there are easier, more direct ways to invest in the AI trend, making healthcare a poor proxy for the theme until its financial impact becomes clear.