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  1. The Full Ratchet (TFR): Venture Capital and Startup Investing Demystified
  2. Investor Stories 472: Think Big, Stay Patient, Earn Access — Venture Advice from Foresite, Mayfield, and Blue Moon (Tananbaum, Chaddha, Orthlieb)
Investor Stories 472: Think Big, Stay Patient, Earn Access — Venture Advice from Foresite, Mayfield, and Blue Moon (Tananbaum, Chaddha, Orthlieb)

Investor Stories 472: Think Big, Stay Patient, Earn Access — Venture Advice from Foresite, Mayfield, and Blue Moon (Tananbaum, Chaddha, Orthlieb)

The Full Ratchet (TFR): Venture Capital and Startup Investing Demystified · Apr 23, 2026

VC experts advise new investors: Focus on home runs, practice patience in company building, and create differentiated access to win deals.

Mayfield's Naveen Chadda: A Single VC Success Can Be a Fluke; True Skill Requires Patience

Company building is a long-term game, not a sprint. A single early success in an investor's career can easily be attributed to luck. True investing prowess is demonstrated through consistent, patient backing of companies over the long haul, understanding that there are no overnight successes in venture capital.

Investor Stories 472: Think Big, Stay Patient, Earn Access — Venture Advice from Foresite, Mayfield, and Blue Moon (Tananbaum, Chaddha, Orthlieb) thumbnail

Investor Stories 472: Think Big, Stay Patient, Earn Access — Venture Advice from Foresite, Mayfield, and Blue Moon (Tananbaum, Chaddha, Orthlieb)

The Full Ratchet (TFR): Venture Capital and Startup Investing Demystified·a day ago

Blue Moon's Ben Orthlieb: 'Differentiated Access' Is a Myth for Building a Sustainable VC Fund

While new investors might gain proprietary access to a handful of deals, this is not a scalable strategy for an entire fund. To succeed long-term, emerging managers must build a system for getting access at scale, as relying on a few unique connections is insufficient to build a top-performing venture fund.

Investor Stories 472: Think Big, Stay Patient, Earn Access — Venture Advice from Foresite, Mayfield, and Blue Moon (Tananbaum, Chaddha, Orthlieb) thumbnail

Investor Stories 472: Think Big, Stay Patient, Earn Access — Venture Advice from Foresite, Mayfield, and Blue Moon (Tananbaum, Chaddha, Orthlieb)

The Full Ratchet (TFR): Venture Capital and Startup Investing Demystified·a day ago

Blue Moon's Ben Orthlieb: New VCs Should Avoid Concentrated Portfolios Due to Adverse Selection

Conventional wisdom tells new VCs to write big checks into a concentrated portfolio. However, this is a flawed strategy because emerging managers often face adverse selection, lacking the access to top-tier deals that established firms have. This makes a concentrated approach dangerously risky for a new fund.

Investor Stories 472: Think Big, Stay Patient, Earn Access — Venture Advice from Foresite, Mayfield, and Blue Moon (Tananbaum, Chaddha, Orthlieb) thumbnail

Investor Stories 472: Think Big, Stay Patient, Earn Access — Venture Advice from Foresite, Mayfield, and Blue Moon (Tananbaum, Chaddha, Orthlieb)

The Full Ratchet (TFR): Venture Capital and Startup Investing Demystified·a day ago

Foresite Capital's Jim Tanenbaum: A VC Fund's Success Relies on Just One or Two 'Hits'

Venture capital returns follow a power law distribution, meaning a fund's entire performance is often determined by one or two massive outliers. New investors should prioritize finding companies with grand-slam potential over building a portfolio of modest, base-hit successes, as it's the big wins that drive everything.

Investor Stories 472: Think Big, Stay Patient, Earn Access — Venture Advice from Foresite, Mayfield, and Blue Moon (Tananbaum, Chaddha, Orthlieb) thumbnail

Investor Stories 472: Think Big, Stay Patient, Earn Access — Venture Advice from Foresite, Mayfield, and Blue Moon (Tananbaum, Chaddha, Orthlieb)

The Full Ratchet (TFR): Venture Capital and Startup Investing Demystified·a day ago