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  1. 99% Invisible
  2. Drug Story: Ivermectin
Drug Story: Ivermectin

Drug Story: Ivermectin

99% Invisible · May 26, 2026

Ivermectin: A miracle cure for parasites, a controversial treatment for COVID. This episode traces the drug's journey from science to belief.

Patients Report Real Benefits from Ineffective Drugs if They Know They're Taking a Medicine

In an 'open label' study, where patients knew they were receiving a treatment, there was a perceived benefit even when the drug was ineffective. This demonstrates how the psychological act of receiving treatment can create a powerful placebo effect, generating compelling but scientifically misleading personal anecdotes.

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Drug Story: Ivermectin

99% Invisible·4 days ago

The CDC is Based in Atlanta Because Parasites, Not Viruses, Were a Primary US Health Threat

The Centers for Disease Control and Prevention's location is a historical relic from its founding mission: combating parasitic diseases like malaria and hookworm that were widespread in the American South 75 years ago. This contradicts the modern perception of the CDC as an agency primarily focused on viral outbreaks.

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Drug Story: Ivermectin

99% Invisible·4 days ago

America's 'Medical Freedom' Movement Originated Over a Century Ago to Oppose Hookworm Eradication

The National League of Medical Freedom, funded by alternative medicine businesses, fought early 20th-century public health initiatives like building outhouses and promoting shoes to stop hookworm. They framed scientific medicine as a 'medical octopus' infringing on personal choice, echoing modern anti-science rhetoric.

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Drug Story: Ivermectin

99% Invisible·4 days ago

A Single Flawed 'Petri Dish' Study Ignited the Global Ivermectin Misinformation Crisis

The Ivermectin-for-COVID theory originated from a lab study showing it killed the virus in a petri dish. Critically, the concentration used was 100 times higher than what's safe for humans. This crucial detail was lost in media headlines like 'Ivermectin kills COVID in 48 hours,' sparking widespread misinformation.

Drug Story: Ivermectin thumbnail

Drug Story: Ivermectin

99% Invisible·4 days ago

Personal Experience Creates Unshakeable Belief That Overrides Conclusive Scientific Evidence

A patient describes feeling 'amazingly improved' just hours after taking Ivermectin for COVID. This powerful personal experience illustrates why large-scale clinical data showing a drug is ineffective often fails to persuade individuals. A compelling anecdote is frequently more powerful to the person who lived it than any statistic.

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Drug Story: Ivermectin

99% Invisible·4 days ago

Political Pressure Can Force Health Agencies To Fund Research Based on Public Belief, Not Scientific Merit

The podcast notes a dangerous shift where political leaders argue that if enough people believe in a treatment, health institutes like the NIH have an 'obligation' to study it. This subverts the scientific process, allowing public opinion and political agendas, rather than prior evidence, to dictate research priorities and funding.

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Drug Story: Ivermectin

99% Invisible·4 days ago

Retracted Scientific Papers With Fake Data Are Still Cited Thousands of Times, Perpetuating Myths

Even after being exposed as fraudulent and retracted, papers from the company 'Surgisphere' claiming Ivermectin's effectiveness against COVID have been cited thousands of times by other researchers. This shows how scientific fraud has a long afterlife, creating a veneer of legitimacy for disproven theories and poisoning the well of knowledge.

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Drug Story: Ivermectin

99% Invisible·4 days ago

Merck's Free Ivermectin Donations Were Subsidized by Its Billion-Dollar Veterinary Drug Sales

While Merck's decision to give away Ivermectin for river blindness is hailed as a philanthropic success, it was financially supported by the drug's massive commercial success as Heartgard for pets. This veterinary version became a top-seller, earning over $1 billion annually, highlighting the business reality behind large-scale corporate charity.

Drug Story: Ivermectin thumbnail

Drug Story: Ivermectin

99% Invisible·4 days ago