/
© 2026 RiffOn. All rights reserved.

Get your free personalized podcast brief

We scan new podcasts and send you the top 5 insights daily.

  1. Business Of Biotech
  2. Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.
Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech · Mar 2, 2026

Vivtex CEO Thomas von Erlach on creating oral biologics, securing a $2.1B Novo Nordisk deal, and leveraging a platform-first strategy.

Vivtex Achieved Profitability by Prioritizing Non-Dilutive Pharma Partnerships Over VC Funding

Unlike many biotech startups reliant on venture capital, Vivtex pursued a different path. By securing around 10 early pharma collaborations, the company generated a substantial stream of non-dilutive revenue, achieving profitability and financial independence far earlier than is typical.

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D. thumbnail

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

Vivtex's $2.1B Novo Nordisk Deal Resulted from Years of Transparent Scientific Engagement

The landmark partnership with Novo Nordisk wasn't won through a sales pitch. It was the result of a multi-year scientific relationship built on transparency. Consistently presenting progress, including failures, at conferences established deep institutional trust and credibility that proved invaluable.

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D. thumbnail

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

Delivering on Partnerships Is More Important Than Securing Them for a Biotech's Reputation

In an industry where technology often fails, Vivtex prioritizes successful execution over deal volume. The CEO stresses that being honest about capabilities and delivering on promises is more crucial for long-term reputation and future partnerships than simply getting an initial deal signed.

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D. thumbnail

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

Biotech Stealth Mode Is for Refining the Technology Offering, Not Just Hiding It

Vivtex's early low profile was a strategic choice to mature its technology and precisely define its value to partners. This 'figuring it out' period allowed them to avoid making a premature public splash with offerings they might later have to retract, ensuring a stronger, more coherent market entry.

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D. thumbnail

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

Vivtex In-Houses All R&D Because CROs Can't Match a Startup's Existential Urgency

Counter to the lean biotech model, Vivtex avoids outsourcing to CROs. The rationale is that only an internal team, whose survival depends on the technology's success, possesses the existential urgency to solve problems at the breakneck pace required—a speed external partners cannot match.

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D. thumbnail

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

MIT's Dr. Langer Steers Scientists from Incremental Research to High-Risk, High-Impact Problems

Dr. Robert Langer's lab culture pushes postdocs beyond their narrow expertise to solve major, riskier problems. This philosophy prioritizes tangible societal and patient benefit over purely academic publications, fostering a unique environment for groundbreaking, commercially-viable innovation.

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D. thumbnail

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

Scientist-CEOs Should Immediately Hire an Operations Pro to Focus on Technical Strategy

Vivtex's scientist-CEO successfully navigated the transition by hiring an experienced finance and operations lead early on. This freed him from learning non-R&D functions from scratch, allowing him to leverage his deep technical expertise for high-value activities like business development and scientific strategy.

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D. thumbnail

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago

Vivtex Spun Out Only After Years of Industry-Focused Validation, Not Just Promising Data

Advised by Dr. Bob Langer, Vivtex's founders understood that academic tech often fails due to insufficient validation. The spin-out was triggered not by initial exciting results, but after years of rigorous validation proving the platform's commercial application in large animal models, a crucial de-risking step.

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D. thumbnail

Making Biologics Orally Available With Vivtex's Thomas von Erlach, Ph.D.

Business Of Biotech·11 hours ago