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  1. The Chain: Protein Engineering Podcast
  2. Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics
Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics

The Chain: Protein Engineering Podcast · Aug 11, 2026

Dr. Janice Reichert chronicles the evolution of antibody therapeutics, the rise of the MABS journal, and key trends shaping the industry's future.

MABS's Flagship "Antibodies to Watch" Series Was Invented to Fill a Submission Gap

The influential "Antibodies to Watch" series wasn't a strategic initiative. Editor Janice Reichert created it herself to fill an issue when authors grew hesitant to submit papers due to a delay in the new journal's PubMed indexing. This crisis-driven solution became a cornerstone of the publication.

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics thumbnail

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics

The Chain: Protein Engineering Podcast·a day ago

China's Biotech Dominance Stems from Deliberate Five-Year Plans and Regulatory Acceleration

China's rise as a biotech power wasn't accidental. It was driven by strategic five-year plans that boosted R&D and manufacturing, and crucially, streamlined regulatory approvals. The time to approve an Investigational New Drug (IND) application dropped from several years to just a few months, fueling rapid development.

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics thumbnail

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics

The Chain: Protein Engineering Podcast·a day ago

The Antibody Society Was Founded Directly After the 2006 TGN1412 Clinical Trial Disaster

The Antibody Society's creation was catalyzed by the shocking 2006 TGN1412 incident, where a first-in-human study nearly killed six participants. This crisis introduced profound uncertainty into the field, prompting founder Jim Houston to establish a focused nonprofit to address the industry's shared concerns and foster collaboration.

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics thumbnail

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics

The Chain: Protein Engineering Podcast·a day ago

A Neutral, Non-Corporate Expert is the Ideal Editor for a Niche Industry Journal

The publisher of MABS specifically sought an editor-in-chief who had a global overview of antibody therapeutics but was not based at a company. This strategy of selecting a neutral, third-party academic researcher ensured the journal would be perceived as reputable, authoritative, and unbiased, which was key to its success.

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics thumbnail

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics

The Chain: Protein Engineering Podcast·a day ago

Early Benchmarking Data on Antibody Success Rates Unlocked Industry Investment

A 2001 report showing humanized antibodies had higher approval success rates than murine versions was a pivotal "eye-opener." While seemingly obvious today, this data, published by a reputable academic group, provided the critical external validation needed at the time to justify major investments into new antibody technologies and development programs.

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics thumbnail

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics

The Chain: Protein Engineering Podcast·a day ago

Prestigious Journals Use a Five-Round Human Evaluation to Combat AI-Generated Papers

To maintain scientific integrity, the journal MABS uses a rigorous five-round manuscript evaluation. This process involves an initial check, an assistant editor assessment, peer review, author revision, and a final editor's polish. This deep, human-led scrutiny serves as a robust filter against low-quality, AI-generated content.

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics thumbnail

Episode: 88 - Janice Reichert on the Evolution of Antibody Therapeutics

The Chain: Protein Engineering Podcast·a day ago